Bai Hong, Li Wei, Asada Yoshihisa, Satou Tadaaki, Wang Yuanshu, Koike Kazuo
Faculty of Pharmaceutical Sciences, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Steroids. 2009 Feb;74(2):198-207. doi: 10.1016/j.steroids.2008.10.007. Epub 2008 Nov 1.
Eleven new 14,15-seco-pregnane-type steroidal glycosides, cynanosides P1-P5, Q1-Q3, R1-R3, and a novel 12,13-seco-14,18-nor-pregnane-type steroidal glycoside, cynanoside S, were isolated from the roots of Cynanchum atratum, together with four known compounds, atratoside C, sublanceoside E3, chekiangensoside C and cynatroside B. Their structures were determined on the basis of spectroscopic analysis and chemical evidence.
从白薇的根中分离出11个新的14,15-断孕甾烷型甾体糖苷，即白薇苷P1 - P5、Q1 - Q3、R1 - R3，以及一个新的12,13-断-14,18-去甲孕甾烷型甾体糖苷，白薇苷S，同时还分离出4个已知化合物，即白薇苷C、细叶白前苷E3、浙江白前苷C和白薇新苷B。通过光谱分析和化学证据确定了它们的结构。
