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1
Competitive repair pathways in immunoglobulin gene hypermutation.
Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):613-9. doi: 10.1098/rstb.2008.0206.
3
The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs.
Mol Cell Biol. 2009 Sep;29(18):5148-57. doi: 10.1128/MCB.00647-09. Epub 2009 Jul 13.
4
Molecular mechanisms of antibody somatic hypermutation.
Annu Rev Biochem. 2007;76:1-22. doi: 10.1146/annurev.biochem.76.061705.090740.
5
Hijacked DNA repair proteins and unchained DNA polymerases.
Philos Trans R Soc Lond B Biol Sci. 2009 Mar 12;364(1517):605-11. doi: 10.1098/rstb.2008.0188.
6
Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases.
DNA Repair (Amst). 2016 Feb;38:110-116. doi: 10.1016/j.dnarep.2015.11.011. Epub 2015 Dec 2.
7
DNA polymerases and somatic hypermutation of immunoglobulin genes.
EMBO Rep. 2005 Dec;6(12):1143-8. doi: 10.1038/sj.embor.7400582.
9
Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.
Eur J Immunol. 2013 Oct;43(10):2765-70. doi: 10.1002/eji.201243191. Epub 2013 Aug 5.
10
UNG shapes the specificity of AID-induced somatic hypermutation.
J Exp Med. 2012 Jul 2;209(7):1379-89. doi: 10.1084/jem.20112253. Epub 2012 Jun 4.

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Base Excision Repair in the Immune System: Small DNA Lesions With Big Consequences.
Front Immunol. 2020 May 29;11:1084. doi: 10.3389/fimmu.2020.01084. eCollection 2020.
3
A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets.
J Exp Med. 2018 Mar 5;215(3):761-771. doi: 10.1084/jem.20171738. Epub 2018 Jan 26.
4
Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs.
J Exp Med. 2017 Apr 3;214(4):1169-1180. doi: 10.1084/jem.20161576. Epub 2017 Mar 10.
5
Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases.
DNA Repair (Amst). 2016 Feb;38:110-116. doi: 10.1016/j.dnarep.2015.11.011. Epub 2015 Dec 2.
6
Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination.
Microbiol Spectr. 2015 Feb;3(1):MDNA3-0037-2014. doi: 10.1128/microbiolspec.MDNA3-0037-2014.
8
Transcriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrity.
Transcription. 2013 May-Jun;4(3):127-35. doi: 10.4161/trns.24556. Epub 2013 Apr 12.
9
AID and Apobec3G haphazard deamination and mutational diversity.
Cell Mol Life Sci. 2013 Sep;70(17):3089-108. doi: 10.1007/s00018-012-1212-1. Epub 2012 Nov 22.
10
Does DNA repair occur during somatic hypermutation?
Semin Immunol. 2012 Aug;24(4):287-92. doi: 10.1016/j.smim.2012.05.002. Epub 2012 Jun 22.

本文引用的文献

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Role of DNA polymerases eta, iota and zeta in UV resistance and UV-induced mutagenesis in a human cell line.
DNA Repair (Amst). 2008 Sep 1;7(9):1551-62. doi: 10.1016/j.dnarep.2008.05.012. Epub 2008 Jul 21.
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Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp.
Cell. 2008 May 16;133(4):601-11. doi: 10.1016/j.cell.2008.02.050.
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Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.
DNA Repair (Amst). 2008 Sep 1;7(9):1603-8. doi: 10.1016/j.dnarep.2008.04.002. Epub 2008 May 16.
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Proteasomal degradation restricts the nuclear lifespan of AID.
J Exp Med. 2008 Jun 9;205(6):1357-68. doi: 10.1084/jem.20070950. Epub 2008 May 12.
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DNA polymerases in adaptive immunity.
Nat Rev Immunol. 2008 Apr;8(4):302-12. doi: 10.1038/nri2281. Epub 2008 Mar 14.
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The strand bias paradox of somatic hypermutation at immunoglobulin loci.
Trends Immunol. 2008 Apr;29(4):167-72. doi: 10.1016/j.it.2008.01.008. Epub 2008 Mar 7.
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Two levels of protection for the B cell genome during somatic hypermutation.
Nature. 2008 Feb 14;451(7180):841-5. doi: 10.1038/nature06547.
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DNA polymerase zeta (pol zeta) in higher eukaryotes.
Cell Res. 2008 Jan;18(1):174-83. doi: 10.1038/cr.2007.117.
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Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.
EMBO J. 2008 Jan 9;27(1):51-61. doi: 10.1038/sj.emboj.7601958. Epub 2007 Dec 13.

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