Ramstack M, Listernick R
Department of Pediatrics, Northwestern University Medical School, Children's Memorial Hospital, Chicago, Illinois 60614.
JPEN J Parenter Enteral Nutr. 1991 Jan-Feb;15(1):89-92. doi: 10.1177/014860719101500189.
Children who are unable to maintain an intake of energy and nutrients adequate to meet their needs for growth and maintenance of nutritional status require modifications in feeding. A new pediatric enteral product (PediaSure) was formulated to meet the nutrient needs of children 1 to 6 years of age in a volume that can be tolerated. We designed a noncontrolled, nonrandomized study to evaluate the suitability of this product in young children with respect to growth, protein status, metabolic responses, and gastrointestinal tolerance. Fourteen chronically disabled children were fed the study formula for 12 weeks, receiving daily at least 90% of their estimated energy requirements. Anthropometric measurements and biochemical parameters were obtained throughout the study period. Weight, weight for age, length, weight index, triceps skin fold thickness, mid-arm circumference, mid-arm muscle circumference, and mid-arm muscle area all increased over the study period. Gastrointestinal tolerance and acceptance of the study formula were excellent; there were no clinically significant changes in the biochemical measurements. This study demonstrates that PediaSure is both safe and efficacious in the maintenance of the nutritional status and the promotion of growth in chronically disabled children who require specialized nutritional support.
无法摄入足够能量和营养以满足其生长及维持营养状况需求的儿童需要调整喂养方式。一种新的儿科肠内产品（沛儿素）被配制出来，其在可耐受的容量下满足1至6岁儿童的营养需求。我们设计了一项非对照、非随机研究，以评估该产品在年幼儿童中对于生长、蛋白质状况、代谢反应及胃肠道耐受性方面的适用性。14名慢性残疾儿童接受该研究配方喂养12周，每日摄入至少90%的估计能量需求。在整个研究期间获取人体测量学指标和生化参数。在研究期间，体重、年龄别体重、身长、体重指数、三头肌皮褶厚度、上臂围、上臂肌肉围及上臂肌肉面积均增加。该研究配方的胃肠道耐受性和接受度良好；生化指标测量无临床显著变化。本研究表明，沛儿素对于需要特殊营养支持的慢性残疾儿童维持营养状况及促进生长既安全又有效。
