Morente Manuel M, Fernández Pedro L, de Alava Enrique
Tumor Bank Unit, Molecular Pathology Programme, Spanish National Cancer Centre, Madrid, Spain.
Semin Diagn Pathol. 2008 Nov;25(4):317-22. doi: 10.1053/j.semdp.2008.07.007.
Biobanking is a new concept with solid bases in traditional pathology, the development of which is mandatory to allow effective translational research to flourish. Biobank activity is developing as a progressively complex young discipline playing a central role in biomedical research. This review analyzes the role of disease-driven biobanks in translational research, focusing on some aspects considered to be crucial for the future development of these institutions and service providers, including dedicated designs, funding, personnel, and ethical and legal frameworks, which, coupled with networked functioning, can provide an endless source of samples and, ideally, associated clinical information for biomedical research.
生物样本库是一个在传统病理学中有坚实基础的新概念，其发展对于促进有效的转化研究蓬勃发展至关重要。生物样本库活动正发展成为一门日益复杂的年轻学科，在生物医学研究中发挥着核心作用。本综述分析了疾病驱动型生物样本库在转化研究中的作用，重点关注对这些机构和服务提供商未来发展至关重要的一些方面，包括专门的设计、资金、人员以及伦理和法律框架，这些方面与网络化运作相结合，可以为生物医学研究提供源源不断的样本以及理想情况下相关的临床信息。
