Shiraz Institute for Cancer Research, School of medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Iran Biomed J. 2020 Jul;24(4):206-13. doi: 10.29252/ibj.24.4.206. Epub 2020 Feb 12.
Biobank, defined as a functional unit for facilitating and improving research by storing biospecimen and their accompanying data, is a key resource for advancement in life science. The history of biobanking goes back to the time of archiving pathology samples. Nowadays, biobanks have considerably improved and are classified into two categories: diseased-oriented and population-based biobanks. UK biobank as a population-based biobank with about half a million samples, Biobank Graz as one of the largest biobanks in terms of sample size, and The International Agency for Research on Cancer biobank as a specialized the World Health Organization cancer agency are few examples of successful biobanks worldwide. The present review provides a history of biobanking, and after presenting different biobanks, we discuss in detail the challenges in the field of biobanking and its future, as well. In the end, ICR biobank, as the first cancer biobank in Iran established in 1998, is thoroughly described.
生物库被定义为通过存储生物样本及其相关数据来促进和改善研究的功能单元，是生命科学发展的关键资源。生物库的历史可以追溯到存档病理学样本的时代。如今，生物库已经有了很大的改进，并分为两类：面向疾病的生物库和基于人群的生物库。英国生物库是一个基于人群的生物库，拥有约 50 万份样本；格拉茨生物库是样本量最大的生物库之一；国际癌症研究机构生物库是世界卫生组织癌症机构的一个专门机构，这些都是全球成功的生物库的几个例子。本综述提供了生物库的历史，在介绍了不同的生物库之后，我们详细讨论了生物库领域的挑战及其未来。最后，我们深入描述了 1998 年在伊朗成立的第一个癌症生物库——ICR 生物库。
