Wong Sui H, Lecky Bryan R F, Hart Ian J, Crooks Daniel, Solomon Tom
The Walton Centre for Neurology and Neurosurgery NHS Trust, Lower Lane, Fazakerley, Liverpool, UK.
J Med Case Rep. 2008 Nov 14;2:344. doi: 10.1186/1752-1947-2-344.
Recurrent myositis triggered by infections is unusual, with only one other case reporting two attacks described in the literature.
We report the case of a 24-year-old Caucasian woman with recurrent myositis triggered by sore throat, respiratory and urinary tract infections, over the past 18 years, up to four times a year. Myositis of this frequency and duration, apparently triggered by infections, has not been reported previously.
We believe that this case adds to the understanding of myositis associated with infections being a triggered autoimmune response, and postulate that the pathogenesis in our patient is a non-specific immune response to a range of different precipitants, both bacterial and viral.
由感染引发的复发性肌炎并不常见,文献中仅另有一例报告了两次发作情况。
我们报告了一名24岁白种女性的病例,在过去18年中,她因喉咙痛、呼吸道和泌尿道感染引发复发性肌炎,每年发作多达四次。如此频繁且持续发作的肌炎,显然由感染引发,此前尚未见报道。
我们认为该病例有助于加深对与感染相关的肌炎是一种触发的自身免疫反应的理解,并推测我们患者的发病机制是对一系列不同的诱发因素(包括细菌和病毒)的非特异性免疫反应。