Medicine, Jacobi Medical Center, Bronx, New York, USA
Rheumatology, Montefiore Hospital and Medical Center, Bronx, New York, USA.
BMJ Case Rep. 2021 Apr 13;14(4):e239457. doi: 10.1136/bcr-2020-239457.
The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected millions of people around the globe. The most common presentation of COVID-19 is fever and upper and lower respiratory tract infection. Myalgia is fairly common in the prodromal phase of the viral illness which self-resolves. There is very scant literature on autoimmune myositis triggered by COVID-19 infection. We report a case of SARS-CoV-2 infection, who presented with progressive muscle weakness with rhabdomyolysis and necrotizing autoimmune myopathy on muscle biopsy. This case report imposes awareness of musculoskeletal autoimmune processes triggered by COVID-19 which requires clinical suspicion for early diagnosis and initiation of treatment.
由 SARS-CoV-2 病毒引起的 COVID-19 大流行已经影响了全球数百万人。COVID-19 的最常见表现是发热和上、下呼吸道感染。肌痛在病毒疾病的前驱期相当常见，会自行缓解。关于 COVID-19 感染引发的自身免疫性肌炎的文献非常少。我们报告了一例 SARS-CoV-2 感染病例，该患者出现进行性肌无力，肌肉活检显示横纹肌溶解和坏死性自身免疫性肌病。本病例报告引起了对 COVID-19 引发的肌肉骨骼自身免疫过程的认识，这需要临床怀疑以进行早期诊断和开始治疗。
