Mortensen Gitte Lee, Larsen Helle Kiellberg
Bispebjerg Hospital, Dermato-venerologisk Afdeling.
Ugeskr Laeger. 2008 Nov 17;170(47):3858-62.
The new quadrivalent vaccine against human papillomavirus (HPV) can prevent a large number of cervical cancer cases and most cases of genital warts. Genital warts are among the most common sexually transmitted diseases in Denmark and constitute a considerable burden to the health care system as well as to the individual patient. The aim of this study is to examine the ways in which genital warts may affect the patient's quality of life. The results are important in relation to treatment as well as counselling of patients suffering from genital warts. The results are particularly relevant to decisions concerning the introduction of HPV vaccination of men as well as women.
A qualitative research design was applied using focus group interviews with male and female genital wart patients aged 18-30 years. The study was based on a literature review which identified the important issues and questions presented to the participants.
The participants in the study have a significantly lowered quality of life due to their genital warts. The disease negatively affects them psychologically, socially and in their sex and love life in particular. The course of treatment is a burden because of the uncertain time-line and the varying effectiveness. There is much need for more information and communication about the disease and its psycho-sexual aspects.
The development of a quadrivalent HPV vaccine is a milestone in the prevention of both cervical cancer and genital warts. The knowledge of genital warts is limited despite the prevalence of the disease and its severe effects on the patient's quality of life. This study indicates that HPV vaccination of both sexes would have a marked positive effect on the mental burden associated with the disease.
新型四价人乳头瘤病毒（HPV）疫苗可预防大量宫颈癌病例以及大多数尖锐湿疣病例。尖锐湿疣是丹麦最常见的性传播疾病之一，给医疗保健系统以及患者个人都带来了相当大的负担。本研究的目的是探讨尖锐湿疣可能影响患者生活质量的方式。研究结果对于尖锐湿疣患者的治疗及咨询具有重要意义。这些结果对于有关男性和女性HPV疫苗接种的决策尤为相关。
采用定性研究设计，对18至30岁的尖锐湿疣男女患者进行焦点小组访谈。该研究基于文献综述，确定了向参与者提出的重要问题。
由于患有尖锐湿疣，本研究中的参与者生活质量显著下降。该疾病在心理、社交方面，尤其是在性和爱情生活方面对他们产生了负面影响。治疗过程是一种负担，因为治疗时间线不确定且疗效各异。对于该疾病及其心理性方面，非常需要更多的信息和沟通。
四价HPV疫苗的研发是预防宫颈癌和尖锐湿疣的一个里程碑。尽管尖锐湿疣患病率高且对患者生活质量有严重影响，但人们对其了解有限。本研究表明，男女HPV疫苗接种将对与该疾病相关的心理负担产生显著的积极影响。
