斯氏按蚊的乙酰胆碱酯酶基因。
The acetylcholinesterase gene of Anopheles stephensi.
作者信息
Hall L M, Malcolm C A
机构信息
Department of Medical Microbiology, London Hospital Medical College, UK.
出版信息
Cell Mol Neurobiol. 1991 Feb;11(1):131-41. doi: 10.1007/BF00712805.
Abstract
- The acetylcholinesterase (AChE) gene from the important malaria vector Anopheles stephensi has been isolated by homology to the Drosophila acetylcholinesterase gene. 2. The complete sequence and intron-exon organization has been determined. The encoded protein has 69% identity to Drosophila AChE and 38 and 36% identity to Torpedo AChE and human butyrylcholinesterase, respectively.
摘要
- 通过与果蝇乙酰胆碱酯酶基因的同源性，已从重要的疟疾传播媒介斯氏按蚊中分离出乙酰胆碱酯酶（AChE）基因。2. 已确定了其完整序列和内含子-外显子结构。编码的蛋白质与果蝇AChE的同一性为69%，与电鳐AChE和人丁酰胆碱酯酶的同一性分别为38%和36%。
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本文引用的文献
1
A catalogue of splice junction sequences.剪接连接序列目录。
Nucleic Acids Res. 1982 Jan 22;10(2):459-72. doi: 10.1093/nar/10.2.459.
2
Organization and expression of eucaryotic split genes coding for proteins.编码蛋白质的真核生物断裂基因的组织与表达。
Annu Rev Biochem. 1981;50:349-83. doi: 10.1146/annurev.bi.50.070181.002025.
3
Cloning of DNA sequences from the white locus of D. melanogaster by a novel and general method.通过一种新颖通用的方法克隆黑腹果蝇白色基因座的DNA序列。
Cell. 1981 Sep;25(3):693-704. doi: 10.1016/0092-8674(81)90176-8.
4
Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing.用核酸外切酶III进行单向消化可为DNA测序创建靶向断点。
Gene. 1984 Jun;28(3):351-9. doi: 10.1016/0378-1119(84)90153-7.
5
The molecular forms of cholinesterase and acetylcholinesterase in vertebrates.脊椎动物体内胆碱酯酶和乙酰胆碱酯酶的分子形式。
Annu Rev Neurosci. 1982;5:57-106. doi: 10.1146/annurev.ne.05.030182.000421.
6
Primary structure of Torpedo californica acetylcholinesterase deduced from its cDNA sequence.从电鳐乙酰胆碱酯酶cDNA序列推导的一级结构
Nature. 1986;319(6052):407-9. doi: 10.1038/319407a0.
7
Complete amino acid sequence of human serum cholinesterase.人血清胆碱酯酶的完整氨基酸序列
J Biol Chem. 1987 Jan 15;262(2):549-57.
8
Eukaryotic protein modification and membrane attachment via phosphatidylinositol.
Cell. 1987 Jan 30;48(2):179-81. doi: 10.1016/0092-8674(87)90419-3.
9
Divergence in primary structure between the molecular forms of acetylcholinesterase.乙酰胆碱酯酶分子形式之间一级结构的差异。
J Biol Chem. 1988 Jan 25;263(3):1140-5.
10
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EMBO J. 1988 Oct;7(10):2983-93. doi: 10.1002/j.1460-2075.1988.tb03161.x.
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