Roth Jakob
Radiologische Physik, Radio-Onkologie, Universitätsspital Basel, Basel, Schweiz.
Strahlenther Onkol. 2008 Oct;184(10):505-9. doi: 10.1007/s00066-008-1866-7. Epub 2008 Oct 1.
Along with the treatment equipment and the planning system the individual doses to the patient also have to be part of quality assurance. To make sure that the dose application to the patient is correct, a two-step concept is used: the check of the planned dose and the in vivo dosimetry.
In contrast to the treatment planning where the necessary parameters for a desirable dose distribution and dose are determined in the target volume, the dose in the ICRU point is calculated from the individual setup parameters. This is done by using an Excel Macro program. Additionally, on the occasion of the first treatment session, the entrance dose on the patient surface is measured for each separate treatment field with a semiconductor diode. This dose is compared to the reference value from the treatment planning.
Given a tolerance level of 4% for the correspondence of the doses in the ICRU point, 2.1% of the photon treatment plans showed a bigger deviation. The tolerance of the deviation of the measured entrance dose from the dose calculated in the treatment planning was set to +/- 5% for photons without wedge and to +/- 10% for photons with wedge or for electrons. 14% of all treatment fields exceeded the given tolerances without taking possible repeated measurements into account. The corresponding figures for photon fields without wedge, with wedge and for electron fields were 19%, 6% and 9%, respectively.
Patient-related checks are essential since transcription and setup errors cannot be excluded. The checks have to be simple, meaningful and unambiguous. One must assume their independence of the individual and the method. If the tolerances are exceeded, actions have to be taken. This has to be taken into account when the tolerances are established.
与治疗设备和计划系统一样,患者的个体剂量也必须作为质量保证的一部分。为确保对患者的剂量施用正确,采用了两步概念:计划剂量检查和体内剂量测定。
与在靶体积中确定理想剂量分布和剂量所需参数的治疗计划不同,ICRU点的剂量是根据个体设置参数计算得出的。这通过使用Excel宏程序来完成。此外,在首次治疗期间,使用半导体二极管对每个单独的治疗野测量患者体表的入射剂量。将该剂量与治疗计划中的参考值进行比较。
在ICRU点剂量对应性的公差水平为4%的情况下,2.1%的光子治疗计划显示出较大偏差。对于无楔形板的光子,测量的入射剂量与治疗计划中计算剂量的偏差公差设定为±5%,对于有楔形板的光子或电子,设定为±10%。在不考虑可能的重复测量的情况下,14%的所有治疗野超出了给定公差。无楔形板、有楔形板的光子野和电子野的相应数字分别为19%、6%和9%。
与患者相关的检查至关重要,因为不能排除转录和设置错误。检查必须简单、有意义且明确。必须假定其独立于个体和方法。如果超出公差,必须采取行动。在确定公差时必须考虑到这一点。