Klinik für Strahlentherapie und Onkologie im Zentrum der Radiologie, Klinikum der Johann Wolfgang Goethe-Universität Frankfurt/Main, Frankfurt am Main, Germany.
Strahlenther Onkol. 2011 May;187(5):316-21. doi: 10.1007/s00066-011-2176-z. Epub 2011 Apr 26.
An electronic portal imaging device (EPID) is used to control for patient setup and positioning during fractionated radiotherapy. Due to the rising complexity and conformity of irradiation techniques, the demand for an accurate verification of the dose delivered to the patient has also increased. The purpose of this study was to investigate a simple guidance for dosimetry with an Elekta iViewGT™ EPID using commercial software modules.
EPID measurements were performed using an Elekta iViewGT™ EPID on a linear accelerator with 6 MV x-ray beam. The EPID signal was studied for reproducibility, as well as characteristics as a function of dose, dose rate, and field size. A series of experiments, comparing the response of the flat panel imager and ionization chamber measurements of dose, determine the parameters for the calibration model. EPID measurements were also compared with calculations of the treatment planning system.
We found a stable response of the EPID signal over a period of 14 months. It showed nonlinearity depending on dose up to 6.8%. There were low oscillations up to 1.2% depending on dose rate. For all fields, the calibrated flat panel profiles match the measured and calculated dose profiles with maximum deviation of 2-3% for the in-field region. In the high gradient areas, higher differences up to 6% were found.
The gamma evaluation indicates good correlation between predicted and acquired EPID images. The EPID-based pretreatment IMRT verification method will help to improve the quality assurance procedure.
电子射野影像装置(EPID)用于控制分次放射治疗中的患者摆位和定位。由于放射技术的复杂性和适形性不断提高,对患者所接受剂量的精确验证的需求也有所增加。本研究旨在探讨使用 Elekta iViewGT™ EPID 和商业软件模块进行简单剂量学验证的方法。
使用 Elekta iViewGT™ EPID 在 6 MV X 射线直线加速器上进行 EPID 测量。研究了 EPID 信号的重现性以及剂量、剂量率和射野大小的函数特性。通过一系列比较平板探测器响应和电离室剂量测量的实验,确定了校准模型的参数。还将 EPID 测量结果与治疗计划系统的计算结果进行了比较。
我们发现 EPID 信号在 14 个月的时间内具有稳定的响应。它表现出非线性,取决于剂量,最高可达 6.8%。取决于剂量率,存在低至 1.2%的低幅度振荡。对于所有射野,校准后的平板轮廓与测量和计算的剂量轮廓相匹配,在射野区域内最大偏差为 2-3%。在高梯度区域,发现更高的差异,最高可达 6%。
伽马评估表明预测和获取的 EPID 图像之间具有良好的相关性。基于 EPID 的 IMRT 预治疗验证方法将有助于提高质量保证程序。