小于胎龄儿的甲状腺功能
Thyroid function in small for gestational age fetuses.
作者信息
Thorpe-Beeston J G, Nicolaides K H, Snijders R J, Felton C V, McGregor A M
机构信息
Harris Birthright Research Centre for Fetal Medicine, Department of Obstetrics and Gynecology, London, United Kingdom.
出版信息
Obstet Gynecol. 1991 May;77(5):701-6.
Thyroid function was studied in fetal blood samples obtained by funipuncture from 49 small for gestational age (SGA) fetuses at 21-38 weeks' gestation. Levels of TSH, thyroxine-binding globulin, thyroxine (T4), free T4, triiodothyronine (T3), and free T3 were compared with those from 62 appropriate for gestational age (AGA) fetuses. Levels of TSH were significantly higher and T4 and free T4 significantly lower in the SGA than in AGA fetuses. Furthermore, there were significant associations between the increase in TSH and decrease in free T4 and the degrees of fetal hypoxemia and acidemia, respectively.
通过脐血穿刺从49例孕21 - 38周的小于胎龄（SGA）胎儿获取胎儿血样，对其甲状腺功能进行了研究。将促甲状腺激素（TSH）、甲状腺素结合球蛋白、甲状腺素（T4）、游离T4、三碘甲状腺原氨酸（T3）和游离T3的水平与62例适于胎龄（AGA）胎儿的相应水平进行了比较。SGA胎儿的TSH水平显著高于AGA胎儿，而T4和游离T4水平则显著低于AGA胎儿。此外，TSH升高与游离T4降低分别与胎儿低氧血症和酸血症的程度存在显著关联。
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