Joshi Sunil C, Liang C M, Lam Y C
School of Mechanical and Aerospace Engineering, Nanyang Technological University, Nanyang Avenue, Singapore 639 798, Republic of Singapore.
J Biomater Sci Polym Ed. 2008;19(12):1611-23. doi: 10.1163/156856208786440460.
In this study, thermal behavior of aqueous solutions of methyl cellulose (MC) at a constant temperature of 50 degrees C was analyzed. Various samples were studied for two consecutive heating-cooling cycles. The experiments with the solutions prepared using cold de-ionized (DI) water showed that the rate of gelation was higher for higher MC concentrations. However, the rate was slower during the first heating-cooling cycle than during the second cycle. The possible reasons behind such observations are discussed. Various MC solutions prepared using hot DI water were studied for understanding the role of the solvent state in the isothermal gelation process. The gelation of these MC solutions started at a lower MC concentration and resulted in a higher gelation rate. The gelation mechanism responsible for such effects is explored and presented. Finally, a gel-indexing method is proposed to provide a quantitative measure of the gelation state of all the MC gels.
在本研究中，分析了甲基纤维素（MC）水溶液在50摄氏度恒温下的热行为。对各种样品进行了连续两个加热-冷却循环的研究。使用冷去离子（DI）水制备溶液的实验表明，MC浓度越高，凝胶化速率越高。然而，第一个加热-冷却循环中的速率比第二个循环中的速率慢。讨论了这些观察结果背后的可能原因。研究了使用热DI水制备的各种MC溶液，以了解溶剂状态在等温凝胶化过程中的作用。这些MC溶液的凝胶化在较低的MC浓度下开始，并导致较高的凝胶化速率。探索并提出了造成这种影响的凝胶化机制。最后，提出了一种凝胶指数方法，以定量测量所有MC凝胶的凝胶化状态。
