Levenson Cathy W, Figueirôa Silvia M
Program in Neuroscience and Department of Nutrition, Food and Exercise Sciences at Florida State University, Tallahassee, Florida 32306-4340, USA.
Nutr Rev. 2008 Dec;66(12):726-9. doi: 10.1111/j.1753-4887.2008.00122.x.
Gestational vitamin D deficiency causes permanent changes in the developing rat brain. Not only does it alter brain gene and protein expression, deficiency disrupts the balance between neuronal stem cell proliferation and programmed cell death in the offspring. These data are particularly relevant in light of new work showing a high prevalence of vitamin D deficiency in humans.
孕期维生素D缺乏会导致发育中的大鼠大脑发生永久性变化。它不仅会改变大脑基因和蛋白质表达，缺乏还会破坏后代神经元干细胞增殖与程序性细胞死亡之间的平衡。鉴于新的研究表明人类维生素D缺乏的患病率很高，这些数据尤其具有相关性。
