Lucas Robyn M, Ponsonby Anne-Louise, Pasco Julie A, Morley Ruth
National Centre for Epidemiology and Population Health, The Australian National University, Canberra, Australia.
Nutr Rev. 2008 Dec;66(12):710-20. doi: 10.1111/j.1753-4887.2008.00126.x.
Current or recent low vitamin D status (or proxy measures such as dietary intake or ambient ultraviolet radiation) is linked to several chronic diseases, including osteoporosis, cancers, and cardiovascular and autoimmune diseases. Low prenatal vitamin D status may also increase susceptibility to such diseases in later life via specific target organ effects and/or through changes to the developing immune system. Maternal vitamin D supplementation during pregnancy could be an important public health measure to decrease risk of a range of chronic diseases, but further research is required to clarify beneficial and adverse effects of high prenatal vitamin D.
目前或近期维生素D水平较低（或诸如饮食摄入或环境紫外线辐射等替代指标）与多种慢性疾病相关，包括骨质疏松症、癌症以及心血管疾病和自身免疫性疾病。孕期维生素D水平较低还可能通过特定靶器官效应和/或发育中免疫系统的变化，增加日后患此类疾病的易感性。孕期补充维生素D可能是降低一系列慢性疾病风险的一项重要公共卫生措施，但需要进一步研究以阐明孕期高剂量维生素D的有益和不良影响。
