Astikainen Piia, Lillstrang Elina, Ruusuvirta Timo
Department of Psychology, University of Jyväskylä, PO Box 35, 40014 Jyväskylä, Finland.
Eur J Neurosci. 2008 Dec;28(11):2319-24. doi: 10.1111/j.1460-9568.2008.06510.x. Epub 2008 Nov 3.
It remains unclear whether the mismatch negativity of event-related potentials (ERPs) in vision resembles its auditory counterpart in terms of memory relatedness. We recorded ERPs to visual bars in adult humans engaged in an auditory task. In one condition, a bar ('standard') repeated at 400- or 1100-ms non-stimulated intervals was rarely (P = 0.1) replaced by another bar of a different orientation ('deviant'). In the other condition (400-ms intervals), the occurrences of the standards were replaced by 10 (P = 0.1 each) bars of different orientations, including that of the deviant ('control-deviant'). Deviants shifted ERPs towards negative polarity relative to standards in occipital electrodes and towards positive polarity in frontal electrodes at 185-205 ms post-stimulus but only when 400-ms non-stimulated intervals were applied. Furthermore, the shift existed even relative to ERPs to control-deviants. The findings suggest that, as in audition, vision supports the detection of voluntarily unattended changes per se within the constraints of sensory memory. The findings also pave the way for the future exploration of both intact and impaired memory-based visual processing and memory capacity.
目前尚不清楚视觉事件相关电位（ERP）中的失配负波在记忆相关性方面是否类似于其听觉对应物。我们记录了参与听觉任务的成年人对视觉条的ERP。在一种情况下，以400毫秒或1100毫秒的非刺激间隔重复出现的条（“标准”）很少（P = 0.1）被另一个不同方向的条（“偏差”）取代。在另一种情况下（400毫秒间隔），标准条的出现被10个（每个P = 0.1）不同方向的条取代，包括偏差条（“对照 - 偏差”）。在刺激后185 - 205毫秒，偏差条相对于标准条使枕叶电极处的ERP向负极性偏移，额叶电极处向正极性偏移，但仅在应用400毫秒非刺激间隔时出现。此外，即使相对于对照 - 偏差条的ERP，这种偏移也存在。研究结果表明，与听觉一样，视觉在感觉记忆的限制范围内支持对自发未注意到的变化本身的检测。这些发现也为未来探索完整和受损的基于记忆的视觉处理及记忆能力铺平了道路。
