Czigler István, Weisz Júlia, Winkler István
Institute for Psychology of the Hungarian Academy of Sciences, Budapest, Hungary.
Neurosci Lett. 2006 Jun 19;401(1-2):178-82. doi: 10.1016/j.neulet.2006.03.018. Epub 2006 Apr 4.
Previous studies showed a visual analogue of the mismatch negativity (MMN) event-related potential (ERP), which is elicited by violating some sensory regularity. Separating physical change from violating a regularity, here we show that the visual MMN (vMMN) is elicited by regularity violations that do not involve physical stimulus change. Adult participants were presented with a series of red-black and green-black checkerboard patterns delivered regularly in an RRGGRRGG ... order. Infrequently (p=0.1) this regularity was broken by repeating a stimulus one additional time (e.g. RRGGRRR). ERPs elicited by irregular stimulus repetitions were negatively displaced compared to those elicited both by regular repetition and regular change in two latency ranges: 100-140 ms and 220-260 ms. Whereas the first of these two negative ERP differences appears to be sensitive to stimulus repetition per se, the second difference can be identified as a vMMN response to violating the sequential regularity. Thus, similarly to its auditory counterpart, vMMN reflects deviance-(regularity-violation) rather than change-detection processes.
先前的研究显示了失配负波（MMN）事件相关电位（ERP）的视觉类似物，它是由违反某些感觉规律引发的。将物理变化与违反规律区分开来，在此我们表明，视觉MMN（vMMN）是由不涉及物理刺激变化的规律违反所引发的。成年参与者被呈现一系列以RRGGRRGG……顺序有规律呈现的红黑和绿黑棋盘图案。偶尔（p = 0.1），通过额外重复一次刺激（例如RRGGRRR）打破这种规律。与由规律重复和规律变化在两个潜伏期范围（100 - 140毫秒和220 - 260毫秒）所引发的ERP相比，由不规则刺激重复所引发的ERP出现负向偏移。虽然这两个负向ERP差异中的第一个似乎对刺激重复本身敏感，但第二个差异可被识别为对违反序列规律的vMMN反应。因此，与其听觉对应物类似，vMMN反映的是偏差（规律违反）而非变化检测过程。
