Schurmans Annelies, Van Calster Joachim, Stalmans Peter
Department of Ophthalmology, University Hospitals Leuven, Belgium.
Am J Ophthalmol. 2009 Mar;147(3):495-500. doi: 10.1016/j.ajo.2008.09.003. Epub 2008 Nov 20.
To evaluate the anatomical and functional outcomes in macular hole (MH) patients who underwent vitrectomy with inner limiting membrane (ILM) peeling, endodrainage, and heavy silicone oil (HSO) endotamponade.
A retrospective case series with 54 consecutive eyes from 53 patients with idiopathic stage 3 or 4 MHs.
Surgery with infracyanine green-assisted ILM peeling and endodrainage was performed. Patients who were phakic underwent a simultaneous phacoemulsification. At the end of the operation, a HSO tamponade was used in all cases. The patient maintained a face-up position for 24 hours postoperatively. The HSO was removed two to three months after initial surgery. Optical coherence tomography was performed preoperatively and postoperatively to determine the MH stage and the anatomical closure rate.
The mean follow-up time was 6.6 months (range, 3.6 to 18.2 months). The overall median duration between the first symptoms and the surgery was four months (range, two to 37 months). The overall anatomical closure success rate after one surgery was 100%. The median preoperative visual acuity (VA) was 20/200 (range, 20/40 to 20/600) and increased to 20/50 (range, 20/20 to 20/300) postoperatively. The median increase in VA was five lines (mean, 4.8 lines; range, -3 to 12 lines). Of all 54 eyes, 30 (55 %) eyes had a final VA of 20/50 or better.
These findings indicate that surgery for MH with ILM peeling, endodrainage, and HSO endotamponade appears to induce a high incidence of anatomical closure with good visual outcome.
评估接受玻璃体切割术联合内界膜(ILM)剥除、内引流及重硅油(HSO)眼内填充的黄斑裂孔(MH)患者的解剖和功能结局。
对53例特发性3或4期MH患者的54只连续眼进行回顾性病例系列研究。
采用吲哚菁绿辅助的ILM剥除和内引流手术。有晶状体眼患者同时行白内障超声乳化术。手术结束时,所有病例均使用HSO填充。患者术后保持面朝上体位24小时。初次手术后两到三个月取出HSO。术前和术后进行光学相干断层扫描以确定MH分期和解剖闭合率。
平均随访时间为6.6个月(范围3.6至18.2个月)。首次症状出现至手术的总体中位持续时间为4个月(范围2至37个月)。一次手术后的总体解剖闭合成功率为100%。术前中位视力(VA)为20/200(范围20/40至20/600),术后提高到20/50(范围20/20至20/300)。VA的中位提高值为5行(平均4.8行;范围-3至12行)。在所有54只眼中,30只(55%)眼最终视力达到20/50或更好。
这些结果表明,采用ILM剥除、内引流及HSO眼内填充治疗MH的手术似乎能诱导较高的解剖闭合率,并获得良好的视觉效果。