Van De Moere Ann, Stalmans Peter
Department of Ophthalmology, UZLeuven, Leuven, Belgium.
Am J Ophthalmol. 2003 Nov;136(5):879-87. doi: 10.1016/s0002-9394(03)00543-9.
To evaluate the anatomical and visual outcome in macular hole patients who underwent surgery with infracyanine green-assisted internal limiting membrane peeling.
A prospective case series with 51 consecutive eyes of 49 patients with idiopathic, iatrogenic, or traumatic Stage 2, 3, or 4 macular holes.
After removing the vitreous, in all eyes infracyanine green-assisted removal of the internal limiting membrane was performed. Patients older than 65 years of age underwent a simultaneous phacoemulsification. At the end of surgery, a silicone oil tamponade was used in all cases, and all patients were asked to position face down for 24 hours. Optical coherence tomography was performed preoperatively and postoperatively to determine the macular hole stage/size and the anatomical closure rate, respectively.
The mean follow-up time was 9.8 months (range, 6-26 months). The overall median duration between the first symptoms and the surgery was 5 months. The overall anatomical success rate after one surgery was 92% (47 eyes), while that of chronic and nonchronic ones was 72.3% and 97.5%, respectively. The median preoperative visual acuity was 20/160 (range, 20/30 to counting fingers) and increased to 20/50 (range, 20/20 to 20/400) postoperatively. The mean increase in visual acuity was 3.7 lines (range, -4 to 10 lines). Of all 51 operated-on eyes, 26 (51%) eyes had a final visual acuity of 20/50 or better.
These findings indicate that infracyanine green-assisted removal of the retinal internal limiting membrane appears to induce a high incidence of anatomical closure, with good visual outcome.
评估接受吲哚菁绿辅助内界膜剥除术的黄斑裂孔患者的解剖学和视觉预后。
对49例患有特发性、医源性或外伤性2、3或4期黄斑裂孔的患者的51只连续眼睛进行前瞻性病例系列研究。
在切除玻璃体后,对所有眼睛进行吲哚菁绿辅助的内界膜剥除术。65岁以上的患者同时进行超声乳化白内障吸除术。手术结束时,所有病例均使用硅油填塞,所有患者均被要求面朝下体位24小时。术前和术后进行光学相干断层扫描,分别确定黄斑裂孔的阶段/大小和解剖学闭合率。
平均随访时间为9.8个月(范围6 - 26个月)。首次症状出现至手术的总体中位持续时间为5个月。一次手术后的总体解剖学成功率为92%(47只眼),慢性和非慢性黄斑裂孔的成功率分别为72.3%和97.5%。术前中位视力为20/160(范围20/30至数指),术后提高到20/50(范围20/20至20/400)。视力平均提高3.7行(范围 - 4至10行)。在所有51只接受手术的眼中,26只(51%)眼的最终视力达到20/50或更好。
这些发现表明,吲哚菁绿辅助的视网膜内界膜剥除术似乎能诱导较高的解剖学闭合率,并具有良好的视觉预后。