Darvin Maxim E, Patzelt Alexa, Knorr Fanny, Blume-Peytavi Ulrike, Sterry Wolfram, Lademann Juergen
Charité-Universitatsmedizin Berlin, Department of Dermatology, Charitéplatz 1, 10117 Berlin, Germany.
J Biomed Opt. 2008 Jul-Aug;13(4):044028. doi: 10.1117/1.2952076.
Variation in the level of the carotenoid antioxidant substances beta-carotene and lycopene in the human skin of ten healthy volunteers was measured with resonance Raman spectroscopy in an in vivo experiment over the course of 12 months. Information on the lifestyle of the volunteers concerning dietary supplementation and stress factors was obtained daily by the completion of questionnaires. The results showed individual variations in the levels of carotenoid antioxidant substances in the skin of the volunteers, which strongly correlated to specific lifestyles, such as the intake of dietary supplementations rich in carotenoids, and the influence of stress factors. A carotenoid-rich nutrition, based on large amounts of fruit and vegetables, increased the measured carotenoid levels of skin, while stress factors such as fatigue, illness, smoking, and alcohol consumption gave rise to a decrease in carotenoid levels of the skin. These decreases occurred relatively quickly over the course of one day, while the subsequent increases lasted for up to 3 days. During the summer and autumn months, an increase in the level of carotenoids in the skin was measured for all volunteers. The average "seasonal increase" of the carotenoid content in the skin was determined to be 1.26-fold.
在一项为期12个月的体内实验中，利用共振拉曼光谱法测量了10名健康志愿者皮肤中类胡萝卜素抗氧化物质β-胡萝卜素和番茄红素水平的变化。通过每日填写问卷，获取了志愿者在饮食补充和压力因素方面的生活方式信息。结果显示，志愿者皮肤中类胡萝卜素抗氧化物质的水平存在个体差异，这与特定的生活方式密切相关，如摄入富含类胡萝卜素的膳食补充剂以及压力因素的影响。基于大量水果和蔬菜的富含类胡萝卜素的营养摄入增加了皮肤中测得的类胡萝卜素水平，而疲劳、疾病、吸烟和饮酒等压力因素则导致皮肤中类胡萝卜素水平下降。这些下降在一天内相对迅速地发生，而随后的增加则持续长达3天。在夏季和秋季月份，所有志愿者皮肤中的类胡萝卜素水平均有所增加。皮肤中类胡萝卜素含量的平均“季节性增加”被确定为1.26倍。
