Strouphauer Emily, Parke Milbrey, Perez-Sanchez Ariadna, Tantry Evelyne, Katta Rajani
Medical Student, Baylor College of Medicine, Houston, TX, USA.
Department of Internal Medicine Resident, Tulane University School of Medicine, New Orleans, LA, USA.
Dermatol Pract Concept. 2023 Oct 1;13(4):e2023256. doi: 10.5826/dpc.1304a256.
Functional foods, defined as whole foods that provide health benefits beyond their nutritional value, may provide multiple dermatologic benefits. Research studies have documented multiple benefits, including enhanced skin barrier function, improved wound healing, radiance, photoprotection, and hormonal regulation. Although the majority of research to date has involved small-scale human interventions or animal models, promising findings have been noted. A number of potential molecular mechanisms have been described, such as the ability of some foods to combat oxidative stress and thus reduce visible and histologic skin changes in response to UV radiation. Additional mechanisms have been described for wound healing, photo-carcinogenesis, and other outcomes. In this review, we discuss the potential dermatologic role of functional foods in order to advocate for larger-scale, evidence-based, human studies to expand this promising field.
功能性食品被定义为除营养价值外还能带来健康益处的天然食品，可能对皮肤有多种益处。研究记录了多种益处，包括增强皮肤屏障功能、改善伤口愈合、提亮肤色、光保护和激素调节。尽管迄今为止的大多数研究都涉及小规模人体干预或动物模型，但已有一些有前景的发现。已经描述了一些潜在的分子机制，例如某些食物对抗氧化应激的能力，从而减少紫外线辐射引起的可见和组织学皮肤变化。还描述了伤口愈合、光致癌作用和其他结果的额外机制。在这篇综述中，我们讨论功能性食品在皮肤病学方面的潜在作用，以倡导开展更大规模、基于证据的人体研究，以拓展这个有前景的领域。
