Sun Lizhong, Qi Ruidong, Chang Qian, Zhu Junming, Liu Yongmin, Yu Chuntao, Zhang Haitao, Lv Bin, Zheng Jun, Tian Liangxin, Lu Jinguo
Department of Cardiovascular Surgery, Cardiovascular Institute and Fuwai Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Ann Thorac Surg. 2008 Dec;86(6):1821-5. doi: 10.1016/j.athoracsur.2008.08.026.
The purpose of the study was to assess the efficacy of total arch replacement combined with stented elephant trunk implantation for Marfan patients with acute Stanford type A aortic dissection involving the aortic arch.
Between January 2004 and April 2006, 13 consecutive Marfan patients (4 female, 9 male) with acute type A aortic dissection involving the aortic arch underwent total arch replacement combined with implantation of a stented elephant trunk. Aortic dissection extending to the iliac artery was seen in 10 patients, and to the abdominal aorta in 3 patients. Ages ranged from 17 to 65 years (mean, 39 +/- 13). Computed tomography was done to evaluate the residual false lumen in the descending aorta.
All patients survived and were discharged from hospital. One patient with thrombosis of the innominate artery suffered cerebral infarction and recovered during follow-up. One patient had ischemia of the left upper limb postoperatively, but recovered after axillary to axillary artery bypass. There was 1 death during the mean follow-up period of 27 +/- 10 months. Complete thrombus formation was observed in 84.6% of patients (11 of 13) around the stented elephant trunk, and in 69.2% of patients (9 of 13) at the diaphragmatic level.
Total arch replacement combined with stented elephant trunk implantation for Marfan patients with acute type A aortic dissection involving the aortic arch results in less late dilatation of the dissected descending aorta. That prolongs the reoperation interval or reduces the number of late thoracoabdominal aortic replacements, unless there is a patent false lumen around the stented elephant trunk.
本研究旨在评估全弓置换联合带支架象鼻术治疗合并主动脉弓部急性 Stanford A 型主动脉夹层的马凡综合征患者的疗效。
2004 年 1 月至 2006 年 4 月,连续 13 例合并主动脉弓部急性 A 型主动脉夹层的马凡综合征患者(4 例女性,9 例男性)接受了全弓置换联合带支架象鼻术植入。10 例患者的主动脉夹层延伸至髂动脉,3 例延伸至腹主动脉。年龄范围为 17 至 65 岁(平均 39±13 岁)。采用计算机断层扫描评估降主动脉内的残余假腔。
所有患者均存活并出院。1 例无名动脉血栓形成患者发生脑梗死,随访期间恢复。1 例患者术后出现左上肢缺血,但在腋动脉至腋动脉旁路手术后恢复。在平均 27±10 个月的随访期内有 1 例死亡。84.6%(13 例中的 11 例)的患者在带支架象鼻周围观察到完全血栓形成,69.2%(13 例中的 9 例)的患者在膈肌水平观察到完全血栓形成。
对于合并主动脉弓部急性 A 型主动脉夹层的马凡综合征患者,全弓置换联合带支架象鼻术植入可减少夹层降主动脉的晚期扩张。这延长了再次手术间隔时间或减少了晚期胸腹主动脉置换的次数,除非带支架象鼻周围存在通畅的假腔。