Zhang Qian, Ma Xiaochun, Zhang Wenlong, Wang Zhengjun, Zhang Haizhou, Zhang Xiaofeng, Song Jian, Zou Chengwei
Department of Cardiovascular Surgery, Shandong Provincial Hospital affiliated to Shandong University, No.324 Jingwu Road, Shandong, 250021, People's Republic of China.
J Cardiothorac Surg. 2017 Oct 3;12(1):86. doi: 10.1186/s13019-017-0649-6.
Aortic dissection (AD) represents a clinically uncommon aortic pathology which predicts a dismal prognosis if not promptly treated. In acute Debakey type I AD (ADIAD), aortic lesion extends from aortic root to even distal abdominal aorta among which aortic arch and its three main branches still remain a great surgical challenge for repair and reconstruction. Several decades have witnessed the painstaking efforts of cardiovascular surgeons across the globe for optimizing the surgical procedures, from total or hemi-arch replacement, "elephant trunk" technique to branched stent graft. However, operative mortality and morbidity still remain to be reduced and surgical strategy is to be advanced and simplified, particularly the repair and reconstruction of aortic arch and supra-aortic vessels.
In this paper, we reviewed the relevant literature concerning recent advances in surgical intervention of aortic arch and summarized our opinions in the application of branched stent graft in ADIAD.
The operative strategy for acute Debakey type I aortic dissection still remain to be advanced and simplified, especially the repair and reconstruction of aortic arch and supra-aortic vessels. For selection of branched stent grafts, the anatomic features and pathological changes of diseased arch are the crucial factors for clinical decision making.
Branched stent graft is potentially an effective alternative for the treatment of type I AD with diseased aortic arch and supra-aortic vessels. The selection of branched stent grafts still remains to be further discussed in large-scale studies in the future.
主动脉夹层(AD)是一种临床少见的主动脉病变,若不及时治疗,预后不佳。在急性德巴基I型主动脉夹层(ADIAD)中,主动脉病变从主动脉根部延伸至腹主动脉远端,其中主动脉弓及其三大主要分支的修复和重建仍是巨大的手术挑战。几十年来,全球心血管外科医生一直在努力优化手术方法,从全弓或半弓置换、“象鼻”技术到分支型支架移植物。然而,手术死亡率和发病率仍有待降低,手术策略有待改进和简化,尤其是主动脉弓和主动脉弓上血管的修复和重建。
本文回顾了有关主动脉弓手术干预最新进展的相关文献,并总结了我们对分支型支架移植物在ADIAD中应用的观点。
急性德巴基I型主动脉夹层的手术策略仍有待改进和简化,尤其是主动脉弓和主动脉弓上血管的修复和重建。对于分支型支架移植物的选择,病变主动脉弓的解剖特征和病理变化是临床决策的关键因素。
分支型支架移植物可能是治疗伴有病变主动脉弓和主动脉弓上血管的I型AD的有效替代方法。分支型支架移植物的选择在未来的大规模研究中仍有待进一步探讨。