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采用非体外循环和主动脉免接触技术对三支血管病变进行全动脉血运重建。

Total arterial revascularization in triple-vessel disease with off-pump and aortic no-touch technique.

作者信息

Kim Wook Sung, Lee Jaejin, Lee Young Tak, Sung Kiik, Yang Ji-Hyuk, Jun Tae-Gook, Park Pyo Won

机构信息

Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

出版信息

Ann Thorac Surg. 2008 Dec;86(6):1861-5. doi: 10.1016/j.athoracsur.2008.06.025.

Abstract

BACKGROUND

We evaluated the outcomes in patients who have undergone total arterial revascularization using the bilateral internal thoracic arteries (BITA) with off-pump and aorta no-touch technique.

METHODS

From March 2001 to September 2007, 512 consecutive patients with triple-vessel disease underwent total arterial revascularization with off-pump and aortic no-touch technique, using BITA or the right gastroepiploic artery (RGEA) in addition to BITA. Only BITA grafts were used for bypass to coronary arteries in 353 patients, and additionally in situ RGEA was bypassed to right coronary arteries in 159 patients. The mean number of distal anastomoses was 4.15 +/- 0.8 per patient.

RESULTS

One 30-day death occurred. Deep sternal wound infection occurred in 2 patients. The rate of perioperative stroke was 0.8%. The patients were followed for as long as 6 years (mean follow-up, 37.9 +/- 17.7 months). The 1-year and 5-year actuarial freedom from cardiac death was 98.3% and 96.7%, respectively. The 1-year and 5-year actuarial freedom from cardiac events was 97.1% and 89.3%, respectively. Using RGEA was a significant predictor of cardiac event-free survival (p = 0.046).

CONCLUSIONS

Total arterial revascularization using off-pump coronary bypass and aortic no-touch techniqe with BITA grafts was safe and effective, with low mortality among patients with triple-vessel disease. Patients undergoing in-situ RGEA grafting for right coronary arteries appeared to have fewer cardiac events than did patients undergoing only BITA grafting in triple-vessel disease.

摘要

背景

我们评估了采用双侧胸廓内动脉(BITA),通过非体外循环和主动脉免接触技术进行全动脉血运重建患者的预后。

方法

从2001年3月至2007年9月,512例连续的三支血管病变患者采用非体外循环和主动脉免接触技术进行全动脉血运重建,使用BITA或除BITA外还使用右胃网膜动脉(RGEA)。353例患者仅使用BITA移植物进行冠状动脉搭桥,另外159例患者还将原位RGEA搭桥至右冠状动脉。每位患者远端吻合的平均数量为4.15±0.8个。

结果

发生1例30天死亡。2例患者发生了深部胸骨伤口感染。围手术期卒中发生率为0.8%。对患者进行了长达6年的随访(平均随访时间为37.9±17.7个月)。1年和5年的心源性死亡精算生存率分别为98.3%和96.7%。1年和5年的无心脏事件精算生存率分别为97.1%和89.3%。使用RGEA是无心脏事件生存的显著预测因素(p = 0.046)。

结论

采用非体外循环冠状动脉搭桥和主动脉免接触技术,使用BITA移植物进行全动脉血运重建是安全有效的,在三支血管病变患者中死亡率较低。在三支血管病变中,接受原位RGEA移植至右冠状动脉的患者似乎比仅接受BITA移植的患者心脏事件更少。

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