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动脉血运重建术——三支血管病变患者的全动脉血运重建术。

The art of arterial revascularization-total arterial revascularization in patients with triple vessel coronary artery disease.

机构信息

Department of Cardiac Surgery, Austin Hospital, Heidelberg, Melbourne, Victoria, Australia.

出版信息

Ann Cardiothorac Surg. 2013 Jul;2(4):543-51. doi: 10.3978/j.issn.2225-319X.2013.07.14.

Abstract

The use of the left internal thoracic artery to graft the left anterior descending artery has been widely accepted as the gold standard for surgical treatment of coronary disease for over 40 years. However the use of multiple other arterial grafts to support this has not been accepted readily, in spite of evidence of superiority over saphenous vein grafts, probably because of perceptions of technical complexity, time constraints for conduit harvesting and increased peri-operative complications. As a result, even today most patients with multivessel coronary artery disease do not receive the potential benefits of extensive or total arterial revascularization. We discuss here the use of contemporary techniques and grafts configurations to simplify this, and the safety and benefit data underpinning this practice. Current patency data confirm that a left internal thoracic artery graft performs well beyond 20 years, with over 80% freedom from failure, but accumulating data suggest that the right internal thoracic artery behaves in the same way. Radial artery grafts are being studied in several randomized trials, but observational studies already suggest a performance which compares favourably with saphenous vein. Total arterial revascularization is achievable in most patients with a small but acceptable increase in risk of sternal complications when certain defined subgroups are excluded.

摘要

左内乳动脉用于前降支的搭桥术已被广泛接受,成为 40 多年来治疗冠心病的金标准。然而,尽管有证据表明其优于大隐静脉桥,其他多种动脉桥的使用并未被广泛接受,可能是因为技术复杂性、获取桥的时间限制和围手术期并发症增加等因素。因此,即使在今天,大多数多支冠状动脉疾病患者也没有从广泛或完全动脉血运重建中获得潜在益处。我们在此讨论使用现代技术和桥接配置来简化这一过程,以及支持这一实践的安全性和益处数据。目前的通畅数据证实,左内乳动脉搭桥术的效果可维持 20 年以上,失败的风险低于 80%,但不断积累的数据表明,右内乳动脉也有类似的表现。桡动脉桥正在几项随机试验中进行研究,但观察性研究已经表明,其性能与大隐静脉桥相比具有优势。在排除某些特定定义的亚组后,大多数患者都可以实现完全的动脉血运重建,但胸骨并发症的风险略有增加。

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