Chang Chin-Chih, Chang Yih-Leong, Lee Yung-Chie
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Ann Thorac Surg. 2008 Dec;86(6):1971-3. doi: 10.1016/j.athoracsur.2008.05.003.
Teratoma with malignant transformation, defined as germ cell tumors with a malignant component of nongerm cell tumors, such as sarcomas and carcinomas, is rarely seen in the mediastinum. A rare case of the mediastinal mature cystic teratoma with focal gastrointestinal adenocarcinoma is described in this report. The patient underwent a video-assisted thoracoscopic surgery for tumor resection. Intraoperatively, the cystic tumor was ruptured due to dense adhesion. The rapid tumor dissemination was postoperatively noted. Careful and complete resection with the cyst wall of the mediastinal mature cystic teratoma intact is necessary to avoid a risk of relapse from a potentially malignant component.
畸胎瘤伴恶性转化，定义为具有非生殖细胞肿瘤恶性成分（如肉瘤和癌）的生殖细胞肿瘤，在纵隔中很少见。本报告描述了一例罕见的纵隔成熟囊性畸胎瘤伴局灶性胃肠道腺癌病例。患者接受了电视辅助胸腔镜手术切除肿瘤。术中，由于粘连紧密，囊性肿瘤破裂。术后发现肿瘤迅速播散。完整切除纵隔成熟囊性畸胎瘤的囊肿壁并仔细操作，对于避免潜在恶性成分复发风险很有必要。
