Buckner Julia D, Turner R Jay
Louisiana State University, Department of Psychology, 236 Audubon Hall, Baton Rouge, LA 70803, USA.
Drug Alcohol Depend. 2009 Feb 1;100(1-2):128-37. doi: 10.1016/j.drugalcdep.2008.09.018. Epub 2008 Nov 20.
Elucidation of mechanisms underlying the high rates of alcohol use disorder (AUD) remains a pressing clinical and research concern. Despite data indicating that social anxiety disorder (SAD) may be a psychological vulnerability that increases AUD risk, no known prospective research has examined underlying mechanisms. Given the nature of SAD, social support and peer alcohol use may be implicated. The present study set out to clarify the SAD-AUD link in several ways using a prospective dataset comprised of 1803 (47% female) young adults at T1, 1431 of whom were assessed again approximately 3 years later. First, stringent criteria were used to directly test whether SAD was a risk for AUD. Second, we examined whether social support and peer alcohol use moderated the prospective SAD-AUD link. Structured diagnostic interviews were conducted to assess DSM-IV Axis I disorders, negative life events, social support, and peer alcohol use. Among men, Time 1 (T1) SAD was not significantly related to Time 2 (T2) AUD. Yet, among women, T1 SAD was related to T2 AUD. Further, T1 SAD was the only internalizing disorder to significantly predict T2 AUD after controlling for relevant variables (e.g., T1 depression, other anxiety, alcohol and marijuana use disorders). The SAD-AUD relation demonstrated directional specificity. Family cohesion and adverse family relations significantly moderated this relation. Findings highlight the important role of SAD and familial support in the onset of AUD among women.
阐明酒精使用障碍(AUD)高发病率背后的机制仍然是一个紧迫的临床和研究问题。尽管有数据表明社交焦虑障碍(SAD)可能是一种增加AUD风险的心理易感性,但尚无已知的前瞻性研究考察其潜在机制。鉴于SAD的性质,社会支持和同伴饮酒可能与之相关。本研究着手通过多种方式阐明SAD与AUD之间的联系,使用了一个前瞻性数据集,该数据集由1803名(47%为女性)处于T1阶段的年轻人组成,其中1431人在大约三年后再次接受评估。首先,使用严格的标准直接检验SAD是否是AUD的风险因素。其次,我们考察了社会支持和同伴饮酒是否调节了SAD与AUD之间的前瞻性联系。通过结构化诊断访谈来评估DSM-IV轴I障碍、负面生活事件、社会支持和同伴饮酒情况。在男性中,T1阶段的SAD与T2阶段的AUD没有显著相关性。然而,在女性中,T1阶段的SAD与T2阶段的AUD相关。此外,在控制了相关变量(如T1阶段的抑郁、其他焦虑症、酒精和大麻使用障碍)后,T1阶段的SAD是唯一能显著预测T2阶段AUD的内化障碍。SAD与AUD之间的关系表现出方向特异性。家庭凝聚力和不良家庭关系显著调节了这种关系。研究结果突出了SAD和家庭支持在女性AUD发病中的重要作用。