Morales Angelica M, Jones Scott A, Kliamovich Dakota, Harman Gareth, Nagel Bonnie J
Department of Psychiatry, Oregon Health & Science University, Portland, OR, USA.
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, OR, USA.
Curr Addict Rep. 2020 Mar;7(1):89-98. doi: 10.1007/s40429-019-00282-y. Epub 2019 Dec 12.
To review prospective longitudinal studies that have identified risk factors for the development of substance use disorders in adulthood from individual differences during childhood and adolescence.
Risk factors during childhood and adolescence that have been consistently linked to increased risk for addiction include externalizing and internalizing symptoms, early substance use, and environmental influences, such as parental behavior and exposure to traumatic experiences.
Since the etiology of substance use disorders is complex and likely is attributable to many causal pathways, systematic examination of the associations between risk factors will be necessary to understand the mixed findings in the existing literature, to determine which individuals should be targeted for prevention efforts, and to design interventions that address risk factors that are most likely to improve outcomes.
回顾前瞻性纵向研究,这些研究从儿童期和青少年期的个体差异中确定了成年后物质使用障碍发展的风险因素。
儿童期和青少年期一直与成瘾风险增加相关的风险因素包括外化和内化症状、早期物质使用以及环境影响,如父母行为和遭受创伤经历。
由于物质使用障碍的病因复杂,可能归因于许多因果途径,因此有必要系统地检查风险因素之间的关联,以理解现有文献中的混合结果,确定哪些个体应作为预防工作的目标,并设计针对最有可能改善结果的风险因素的干预措施。