从海洋海绵直立扁枝螅的抗有丝分裂提取物中分离得到的基于半日花烷的代谢产物。

Scalarane-based metabolites isolated from the antimitotic extract of the marine sponge Hyrtios erectus.

作者信息

Díaz-Marrero Ana R, Matainaho Teatulohi, van Soest Rob, Roberge Michel, Andersen Raymond J

机构信息

Department of Chemistry, University of British Columbia, Vancouver, Canada.

出版信息

Nat Prod Res. 2008;22(15):1304-9. doi: 10.1080/14786410701824023.

DOI:10.1080/14786410701824023

PMID:19023786

Abstract

Two novel sesterterpenes, 1 and 3, containing a scalarane-based framework, have been isolated from the sponge Hyrtios erectus collected in Papua New Guinea. Their structures and relative stereochemistry have been elucidated by analysis of their spectroscopic data.

摘要

从采集自巴布亚新几内亚的海绵直立希氏海绵（Hyrtios erectus）中分离出了两种新型的含有半日花烷骨架的倍半萜，即化合物1和3。通过对其光谱数据的分析阐明了它们的结构和相对立体化学。