Vega William A, Canino Glorisa, Cao Zhun, Alegria Margarita
David Geffen School of Medicine-UCLA, Los Angeles, CA 90024-4142, USA.
Drug Alcohol Depend. 2009 Feb 1;100(1-2):32-8. doi: 10.1016/j.drugalcdep.2008.08.018. Epub 2008 Nov 22.
To examine the population prevalence, patterns of onset, and important demographic covariates for dual (co-occurring) diagnoses of substance and non-substance mental disorders.
A nationally representative sample of U.S. Latino adults was interviewed face-to-face.
Estimates were made using data from the National Latino and Asian Services Survey (NLAAS) using the World Health Organization CIDI, DSM-IV criteria, for case ascertainment.
U.S. born Latinos are much more likely to report a dual diagnoses than are foreign born Latinos in both sexes; 16.88% vs. 5.02% for males (p<0.000), and 7.48% vs. 0.58% for women (p<.000). Total dual diagnoses prevalence was 6.79%, with non-substance mental disorder occurring first 70% of the time, with an earlier age of onset for U.S. Latinos. Immigrants were less likely to be positive for dual diagnoses (OR=0.234, p=<0.0001), or any substance disorder diagnosis (OR=0.261, p=<.0001), if they reported lifetime substance use when compared to U.S. born Latinos.
Latino adults residing in the U.S. have one-fourth the risk of dual diagnoses compared to the U.S. population. Most of this difference is accounted for by lower rates of substance and non-substance disorders and a lower propensity for progression from substance use to substance use disorders, combined with a later age of onset for mental disorders among immigrants. Immigrant women rarely reported dual diagnoses. We recommend bio-behavioral models and transnational studies to identify life course factors contributing to dual diagnoses among U.S. born Latinos.
研究物质使用障碍与非物质使用精神障碍双重(共病)诊断的人群患病率、发病模式及重要的人口统计学协变量。
对具有全国代表性的美国拉丁裔成年人样本进行面对面访谈。
使用来自《美国国家拉丁裔和亚裔服务调查》(NLAAS)的数据,依据世界卫生组织复合国际诊断访谈表(CIDI)及《精神疾病诊断与统计手册》第四版(DSM-IV)标准进行病例确诊,并据此进行估算。
在美国出生的拉丁裔男女报告双重诊断的可能性远高于外国出生的拉丁裔;男性分别为16.88%和5.02%(p<0.000),女性分别为7.48%和0.58%(p<.000)。双重诊断的总患病率为6.79%,70%的情况是非物质使用精神障碍先出现,且美国拉丁裔的发病年龄更早。与在美国出生的拉丁裔相比,如果移民报告有终生物质使用情况,那么他们双重诊断呈阳性的可能性较小(优势比=0.234,p=<0.0001),被诊断为任何物质使用障碍的可能性也较小(优势比=0.261,p=<.0001)。
居住在美国的拉丁裔成年人双重诊断的风险是美国人群的四分之一。这种差异主要是由于物质使用障碍和非物质使用障碍的发病率较低,以及从物质使用发展为物质使用障碍的倾向较低,再加上移民中精神障碍的发病年龄较晚。移民女性很少报告双重诊断。我们建议采用生物行为模型和跨国研究来确定导致在美国出生的拉丁裔双重诊断的生命历程因素。