Trounce J Q, Rutter N, Mellor D H
Department of Child Health, University Hospital, Nottingham.
Dev Med Child Neurol. 1991 Mar;33(3):261-6. doi: 10.1111/j.1469-8749.1991.tb05116.x.
Three boys with hemimegalencephaly are reported. Two suffered neonatal convulsions and the third presented with seizures at seven months. In each case the EEG was grossly abnormal, with spike and wave activity. All three have significant developmental delay and demonstrate other manifestations of the condition: macrocephaly in two, contralateral hemiparesis in one and one boy has ipsilateral facial hemihypertrophy and linear naevus. Hemimegalencephaly can be recognised on cranial ultrasonography, and the seizures may respond to benzodiazepine therapy.
报告了三例半侧巨脑症男孩。其中两例有新生儿惊厥，第三例在七个月时出现癫痫发作。每例患者脑电图均明显异常，有棘波和慢波活动。三例均有明显发育迟缓，并表现出该病症的其他表现：两例有巨头畸形，一例有对侧偏瘫，一例男孩有同侧面部半侧肥大和线状痣。半侧巨脑症可通过头颅超声检查识别，癫痫发作可能对苯二氮䓬类药物治疗有反应。
