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半侧巨脑畸形与正常智力发育。

Hemimegalencephaly and normal intellectual development.

作者信息

Fusco L, Ferracuti S, Fariello G, Manfredi M, Vigevano F

机构信息

Bambino Gesù Children's Hospital, National Medical Research Institute, Rome, Italy.

出版信息

J Neurol Neurosurg Psychiatry. 1992 Aug;55(8):720-2. doi: 10.1136/jnnp.55.8.720.

DOI:10.1136/jnnp.55.8.720
PMID:1326602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC489213/
Abstract

Hemimegalencephaly is a rare congenital malformation characterised by overgrowth of one hemisphere. Although it is commonly thought to be associated with neurological deficits, developmental delay, and intractable epilepsy, the clinical expression of hemimegalencephaly, can vary widely. This patient was neurologically and neuropsychologically normal apart from rare partial seizures.

摘要

半侧巨脑畸形是一种罕见的先天性畸形,其特征为一侧半球过度生长。尽管通常认为它与神经功能缺损、发育迟缓及难治性癫痫有关,但半侧巨脑畸形的临床表现差异很大。除了偶尔的部分性发作外,该患者的神经及神经心理功能均正常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0c3/489213/27ca8efc82f3/jnnpsyc00493-0086-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0c3/489213/27ca8efc82f3/jnnpsyc00493-0086-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f0c3/489213/27ca8efc82f3/jnnpsyc00493-0086-a.jpg

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本文引用的文献

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半侧巨脑症中癫痫从婴儿期到成年期的演变:病例报告及文献综述
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Hemimegalencephaly without epilepsy: case report.无癫痫的半侧巨脑症:病例报告
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Malformations of cortical development and epilepsy.皮质发育畸形与癫痫。
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Hemimegalencephaly: clinical implications and surgical treatment.半侧巨脑症:临床意义与外科治疗
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Electroencephalographic aspects of hemimegalencephaly.半侧巨脑症的脑电图特征
Dev Med Child Neurol. 1989 Jun;31(3):377-83.
7
Hemimegalencephaly and intractable epilepsy: benefits of hemispherectomy.半侧巨脑症与难治性癫痫:大脑半球切除术的益处
Epilepsia. 1989 Nov-Dec;30(6):833-43. doi: 10.1111/j.1528-1157.1989.tb05347.x.
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Lissencephaly (agyria-pachygyria): clinical findings and serial EEG studies.
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Unilateral megalencephaly: correlation of MR imaging and pathologic characteristics.单侧巨脑症:磁共振成像与病理特征的相关性
AJNR Am J Neuroradiol. 1990 May;11(3):523-31.