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一种治疗晚期卵巢癌患者的技术。

A technique for managing terminally ill ovarian carcinoma patients.

作者信息

Chapman C, Bosscher J, Remmenga S, Park R, Barnhill D

机构信息

Department of Obstetrics and Gynecology, Walter Reed Army Medical Center, Washington, D.C. 20307.

出版信息

Gynecol Oncol. 1991 Apr;41(1):88-91. doi: 10.1016/0090-8258(91)90262-4.

Abstract

A patient with terminal ovarian carcinoma was admitted with malnutrition, abdominopelvic pain, and an inoperable complete small bowel obstruction after failing standard therapy and several experimental regimens for her disease. Despite this serious situation, she had an overall high performance status. Instead of administering intravenous narcotics, providing nasogastric suction, and giving other supportive care to make her apparently imminent death as comfortable as possible, her malnutrition was treated with total parenteral nutrition administered through an indwelling central venous catheter during the night hours only. The pain was successfully treated with an indwelling epidural catheter with the continuous infusion of morphine through a portable pump carried by a shoulder strap. The intestinal obstruction was relieved by a percutaneous endogastric tube which drained spontaneously into a leg bag. This regimen allowed the patient complete daytime mobility. She remained active, largely at home, with slowly progressing tumor until her death 9 months after the institution of this supportive care.

摘要

一名晚期卵巢癌患者因营养不良、腹盆腔疼痛以及在标准治疗和针对其疾病的几种实验方案均失败后出现无法手术的完全性小肠梗阻而入院。尽管情况严重,但她的总体身体状况良好。她没有接受静脉注射麻醉剂、胃肠减压以及其他支持性护理以尽可能舒适地度过看似即将到来的死亡,而是仅在夜间通过留置中心静脉导管进行全胃肠外营养来治疗营养不良。通过留置硬膜外导管并使用肩带携带的便携式泵持续输注吗啡成功治疗了疼痛。经皮胃内管使肠梗阻得到缓解,该管自行排入腿袋。这种治疗方案使患者在白天能够完全活动。她一直保持活跃,大部分时间在家中,肿瘤缓慢进展,直至在这种支持性护理实施9个月后去世。

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