Roque Pedro, Mankin Henry J, Rosenberg Andrew
Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Chir Organi Mov. 2008 Dec;92(3):149-54. doi: 10.1007/s12306-008-0060-5. Epub 2008 Nov 15.
Adamantinoma is a rare tumour, which most often affects the tibia and produces lytic and sometimes destructive lesions, which can cause fractures. The lesions occur principally in adults and are more common in males. A small percentage of the patients develop metastases, sometimes quite late in the course. Our institution has treated 42 patients with adamantinomas since 1972 and has evaluated them by imaging studies and histology. The majority of the patients were treated by resection of the lesion and insertion of an intercalary allograft. Only three of the patients died of disease with the time until death ranging from 10 to 17 years. Recurrence occurred in only three patients and the allograft success rate in terms of function was 71% at a mean time of 10 years.
成釉细胞瘤是一种罕见的肿瘤，最常累及胫骨，产生溶骨性病变，有时还会出现破坏性病变，可导致骨折。这些病变主要发生在成年人中，男性更为常见。一小部分患者会发生转移，有时在病程后期才出现。自1972年以来，我们机构共治疗了42例成釉细胞瘤患者，并通过影像学检查和组织学对他们进行了评估。大多数患者接受了病变切除和植入节段性同种异体骨治疗。只有3例患者死于该疾病，死亡时间为10至17年。仅3例患者出现复发，平均10年时同种异体骨的功能成功率为71%。
