van der Schaaf Marike, Dettling Daniela S, Beelen Anita, Lucas Cees, Dongelmans Dave A, Nollet Frans
Department of Rehabilitation, Academic Medical Center, University of Amsterdam, The Netherlands.
Disabil Rehabil. 2008;30(23):1812-8. doi: 10.1080/09638280701673559.
To evaluate the functional status of patients within the first week of discharge from an intensive care unit (ICU), and to identify predictors and explanatory factors of functional status.
A prospective, observational, cohort study was conducted with consecutive ICU patients who had stayed in a mixed, closed-format, university-level ICU for longer than 48 h.
Between 3 and 7 days of discharge from the ICU, functional status (as primary outcome), walking ability, muscle strength, and sensory and cognitive functioning were assessed in 69 survivors. The overall functional status was poor (median Barthel Index 6). In their ability to perform basic activities of daily living, 67% percent were severely dependent, 15% were moderately dependent, and 9% were slightly dependent on other people. Independent walking was impossible for 73% of participants, grip strength was reduced for 50%, and 30% had cognitive impairments. Duration of ventilation was associated with functional status after ICU discharge. Reduced grip strength and walking ability were identified as explanatory factors for poorer functional status shortly after discharge from the ICU.
In the first week after discharge from the ICU, the majority of the patients had substantial functional disabilities in activities of daily living. These disabilities were more severe in patients who experienced ventilation for a longer period of time. There is a need for prospective studies focusing on functional recovery to support informed decision-making concerning the care of critically ill patients after ICU discharge.
评估重症监护病房(ICU)出院后第一周内患者的功能状态,并确定功能状态的预测因素和解释因素。
对连续入住混合型、封闭式大学级ICU超过48小时的ICU患者进行了一项前瞻性观察队列研究。
在从ICU出院后的3至7天,对69名幸存者的功能状态(作为主要结局)、行走能力、肌肉力量以及感觉和认知功能进行了评估。总体功能状态较差(Barthel指数中位数为6)。在进行日常生活基本活动的能力方面,67%的患者严重依赖他人,15%为中度依赖,9%为轻度依赖他人。73%的参与者无法独立行走,50%的人握力下降,30%的人有认知障碍。通气时间与ICU出院后的功能状态相关。握力和行走能力下降被确定为ICU出院后不久功能状态较差的解释因素。
在从ICU出院后的第一周,大多数患者在日常生活活动中存在严重的功能障碍。在经历较长时间通气的患者中,这些障碍更为严重。需要开展侧重于功能恢复的前瞻性研究,以支持就ICU出院后重症患者的护理做出明智决策。