Pinotti H W, Felix V N, Zilberstein B, Cecconello I
Department of Gastroenterology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
World J Surg. 1991 Mar-Apr;15(2):198-204. doi: 10.1007/BF01659053.
Three surgical complications of Chagas' disease--megaesophagus, achalasia of the pylorus, and cholelithiasis--were evaluated within the framework of the experience acquired in the management of 840 cases of megaesophagus--722 in the nonadvanced stage of the disease and 118 with advanced disease (dolichomegaesophagus). In the group of the 722 patients with nonadvanced disease, achalasia of the pylorus was present in 140 (19.4%), and in the total of 840 patients, uncomplicated cholelithiasis without chagasic involvement of the gallbladder and/or papilla was observed in 58 (6.9%). The 722 subjects with nonadvanced megaesophagus were submitted to wide esophagocardiomyectomy performed at the level of the anterior esophagogastric junction, combined with an antireflux valvuloplasty procedure. We recorded no mortality, and 95% excellent and good results in long-term follow-up. On the other hand, dolichomegaesophagus required esophageal resection with reconstruction by means of an esophagogastroplasty placed in the esophageal bed. The mortality rate was 4.2% (5/118); the main postoperative complications were pleural effusion (22%) and fistulas of the esophagogastric anastomosis (8.4%). Postoperatively, the patients adapted well to their new anatomy and gained weight. Achalasia of the pylorus was confirmed by delayed gastric emptying time. This entity was managed by concomitant antropyloromyectomy without mortality. Cholelithiasis was managed by cholecystectomy and radiologic exploration of the bile ducts.
在对840例巨食管病例(疾病非晚期722例,晚期疾病即冗长巨食管118例)的治疗经验框架内,评估了恰加斯病的三种手术并发症——巨食管、幽门失弛缓症和胆石症。在722例疾病非晚期患者组中,140例(19.4%)存在幽门失弛缓症;在840例患者总数中,58例(6.9%)观察到无胆囊和/或乳头恰加斯病累及的单纯胆石症。722例非晚期巨食管患者接受了在前食管胃交界处水平进行的广泛食管贲门肌层切除术,并联合抗反流瓣膜成形术。我们记录到无死亡病例,长期随访中有95%的优良结果。另一方面,冗长巨食管需要进行食管切除术,并通过置于食管床的食管胃成形术进行重建。死亡率为4.2%(5/118);主要术后并发症为胸腔积液(22%)和食管胃吻合口瘘(8.4%)。术后,患者很好地适应了新的解剖结构并体重增加。幽门失弛缓症通过胃排空延迟时间得以证实。该病症通过同时进行的胃幽门肌层切除术进行治疗,无死亡病例。胆石症通过胆囊切除术和胆管的放射学探查进行治疗。