环磷酸腺苷在成年和新生小鼠皮肤中的积累：对缺血和异丙肾上腺素的反应。
Accumulation of cyclic adenosine 3',5'-monophosphate in adult and newborn mouse skin: responses to ischemia and isoproterenol.
作者信息
Murray A W, Solanki V, Verma A K
出版信息
J Invest Dermatol. 1977 Mar;68(3):125-7. doi: 10.1111/1523-1747.ep12492238.
PMID:190327
Abstract
Levels of cyclic adenosine 3',5'-monophosphate in adult mouse skin pieces were rapidly increased on incubation at 37 degrees C, or on exposure to isoproterenol. Accumulation of the cyclic nucleotide under both conditions was greatly decreased in newborn mouse skin, or in adult skin treated with the tumor promotor 12-0-tetradecanoyl-phorbol-13-acetate.
摘要
成年小鼠皮肤切片中的环磷腺苷水平在37℃孵育时或暴露于异丙肾上腺素时会迅速升高。在这两种情况下，环核苷酸的积累在新生小鼠皮肤中或在用肿瘤促进剂12-0-十四酰佛波醇-13-乙酸酯处理的成年皮肤中会大大降低。
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