Leung Dominic Y, Boyd Anita, Ng Arnold A, Chi Cecilia, Thomas Liza
Liverpool Hospital, University of New South Wales, Sydney, New South Wales, Australia.
Am Heart J. 2008 Dec;156(6):1056-64. doi: 10.1016/j.ahj.2008.07.021. Epub 2008 Oct 2.
Left atrial (LA) volume has recently been identified as a potential biomarker for cardiac and cerebrovascular disease. However, evidence regarding the prognostic implications of LA volume still remains unclear. Evaluation of LA size and function using traditional and more recent echocardiographic parameters is potentially feasible in the routine clinical setting. This review article discusses the conventional and newer echocardiographic parameters used to evaluate LA size and function. Conventional parameters include the assessment of phasic atrial activity using atrial volume measurements, transmitral Doppler peak A velocity, atrial fraction, and the atrial ejection force. Newer parameters include Doppler tissue imaging (DTI) including segmental atrial function assessment using color DTI, strain, and strain rate. In addition, an overview of the implications and clinical relevance of the findings of an enlarged left atrium, from currently available literature, is presented.
左心房（LA）容积最近已被确定为心脏和脑血管疾病的潜在生物标志物。然而，关于LA容积预后意义的证据仍不明确。在常规临床环境中，使用传统及更新的超声心动图参数评估LA大小和功能可能是可行的。这篇综述文章讨论了用于评估LA大小和功能的传统及更新的超声心动图参数。传统参数包括使用心房容积测量、二尖瓣血流频谱A峰速度、心房分数和心房射血力来评估心房的阶段性活动。更新的参数包括多普勒组织成像（DTI），其中使用彩色DTI、应变和应变率进行节段性心房功能评估。此外，本文还概述了目前现有文献中关于左心房扩大的研究结果的意义和临床相关性。
