Kao Tzu-Jen, Boverman Gregory, Kim Bong Seok, Isaacson David, Saulnier Gary J, Newell Jonathan C, Choi Myoung H, Moore Richard H, Kopans Daniel B
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.
IEEE Trans Med Imaging. 2008 Dec;27(12):1762-8. doi: 10.1109/TMI.2008.926049.
It has been known for some time that many tumors have a significantly different conductivity and permittivity from surrounding normal tissue. This high "contrast" in tissue electrical properties, occurring between a few kilohertz and several megahertz, may permit differentiating malignant from benign tissues. Here we show the ability of electrical impedance spectroscopy (EIS) to roughly localize and clearly distinguish cancers from normal tissues and benign lesions. Localization of these lesions is confirmed by simultaneous, in register digital breast tomosynthesis (DBT) mammography or 3-D mammograms.
一段时间以来,人们已经知道许多肿瘤的电导率和电容率与周围正常组织有显著差异。在几千赫兹到几兆赫兹之间出现的这种组织电学特性的高“对比度”,可能有助于区分恶性组织和良性组织。在这里,我们展示了电阻抗光谱(EIS)粗略定位并清晰区分癌症与正常组织及良性病变的能力。这些病变的定位通过同步的、配准的数字乳腺断层合成(DBT)乳房X线摄影或三维乳房X线摄影得以确认。