Hubbard T J P, Aken B L, Ayling S, Ballester B, Beal K, Bragin E, Brent S, Chen Y, Clapham P, Clarke L, Coates G, Fairley S, Fitzgerald S, Fernandez-Banet J, Gordon L, Graf S, Haider S, Hammond M, Holland R, Howe K, Jenkinson A, Johnson N, Kahari A, Keefe D, Keenan S, Kinsella R, Kokocinski F, Kulesha E, Lawson D, Longden I, Megy K, Meidl P, Overduin B, Parker A, Pritchard B, Rios D, Schuster M, Slater G, Smedley D, Spooner W, Spudich G, Trevanion S, Vilella A, Vogel J, White S, Wilder S, Zadissa A, Birney E, Cunningham F, Curwen V, Durbin R, Fernandez-Suarez X M, Herrero J, Kasprzyk A, Proctor G, Smith J, Searle S, Flicek P
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.
Nucleic Acids Res. 2009 Jan;37(Database issue):D690-7. doi: 10.1093/nar/gkn828. Epub 2008 Nov 25.
The Ensembl project (http://www.ensembl.org) is a comprehensive genome information system featuring an integrated set of genome annotation, databases, and other information for chordate, selected model organism and disease vector genomes. As of release 51 (November 2008), Ensembl fully supports 45 species, and three additional species have preliminary support. New species in the past year include orangutan and six additional low coverage mammalian genomes. Major additions and improvements to Ensembl since our previous report include a major redesign of our website; generation of multiple genome alignments and ancestral sequences using the new Enredo-Pecan-Ortheus pipeline and development of our software infrastructure, particularly to support the Ensembl Genomes project (http://www.ensemblgenomes.org/).
Ensembl项目(http://www.ensembl.org)是一个全面的基因组信息系统,其特点是为脊索动物、选定的模式生物和疾病载体基因组提供一套集成的基因组注释、数据库及其他信息。截至第51版(2008年11月),Ensembl全面支持45个物种,另有3个物种有初步支持。过去一年新增的物种包括红毛猩猩和另外6个低覆盖度的哺乳动物基因组。自我们上次报告以来,Ensembl的主要新增内容和改进包括对网站进行重大重新设计;使用新的Enredo-Pecan-Ortheus管道生成多个基因组比对和祖先序列,以及开发我们的软件基础设施,特别是为支持Ensembl Genomes项目(http://www.ensemblgenomes.org/)。