European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
Department of Biointeractions and Crop Protection, Rothamsted Research, Harpenden, Hertfordshire AL5 2JQ, UK.
Nucleic Acids Res. 2020 Jan 8;48(D1):D689-D695. doi: 10.1093/nar/gkz890.
Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the context of the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of interfaces to genomic data across the tree of life, including reference genome sequence, gene models, transcriptional data, genetic variation and comparative analysis. Data may be accessed via our website, online tools platform and programmatic interfaces, with updates made four times per year (in synchrony with Ensembl). Here, we provide an overview of Ensembl Genomes, with a focus on recent developments. These include the continued growth, more robust and reproducible sets of orthologues and paralogues, and enriched views of gene expression and gene function in plants. Finally, we report on our continued deeper integration with the Ensembl project, which forms a key part of our future strategy for dealing with the increasing quantity of available genome-scale data across the tree of life.
Ensembl Genomes(http://www.ensemblgenomes.org)是一个整合的非脊椎动物物种基因组规模数据资源,补充了在 Ensembl 项目(http://www.ensembl.org)背景下开发的脊椎动物基因组学资源。这两个资源共同提供了跨越生命之树的基因组数据的一致接口集,包括参考基因组序列、基因模型、转录数据、遗传变异和比较分析。可以通过我们的网站、在线工具平台和编程接口访问数据,每年更新四次(与 Ensembl 同步)。在这里,我们将重点介绍最近的发展情况,概述 Ensembl Genomes。这些包括持续增长、更稳健和可重复的同源物和同系物集,以及植物中基因表达和基因功能的丰富视图。最后,我们报告了我们与 Ensembl 项目的持续深度整合,这是我们未来应对生命之树中可用基因组规模数据不断增加的战略的关键部分。