Ram Rapur, Swarnalatha Guditi, Varma Vibha, Desai Madhav, Prasad Neela, Sastry Regulagadda A, Dakshinamurty Kaligotla V
Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad - India.
J Nephrol. 2008 Nov-Dec;21(6):962-4.
A 42-year-old continuous ambulatory peritoneal dialysis patient had presented to us with symptoms and signs of peritonitis, complicated by intestinal obstruction. On fourth day after admission, the Tenckhoff catheter was removed, as there was no response to intraperitoneal antibiotic. He developed hypotension during one of the hemodialysis sessions and was found to have low hemoglobin of 4 g/dL. Computed tomography revealed high-density fluid suggestive of fresh blood and clots in the peritoneal cavity. Conventional visceral angiogram with selective inferior mesenteric arterial cannulation revealed pseudoaneurysm arising from the descending branch of the left colic artery. An effort to embolize the pseudoaneurysm failed on 2 occasions. At laparotomy the pseudoaneurysm of the left colic artery was identified after evacuation of blood clots. The pseudoaneurysm was then excised and a lateral rent in the descending branch of left colic artery was repaired. The pus showed septate hyphae on potassium hydroxide mount. He was treated with injections of amphotericin B and oral voriconazole as the culture showed growth of Aspergillus flavus. The early fibrinous, ''easy'' flimsy adhesions formed during the initial intestinal obstruction phase might have resulted in formation of the pseudoaneurysm when the Tenckhoff catheter was removed with traction. The removal of the Tenckhoff catheter, drop in hemoglobin and distension of the abdomen were temporally so closely related that the pseudoaneurysm as a result of the traction removal of the catheter was undeniable. A controlled trial would provide firm evidence either in favor or against formal dissection for the removal of Tenckhoff catheters.
一名42岁的持续性非卧床腹膜透析患者因腹膜炎症状和体征前来就诊,并发肠梗阻。入院后第四天,由于腹膜内使用抗生素无效,Tenckhoff导管被拔除。他在一次血液透析过程中出现低血压,血红蛋白低至4g/dL。计算机断层扫描显示腹腔内有高密度液体,提示有新鲜血液和血凝块。经选择性肠系膜下动脉插管的传统内脏血管造影显示,左结肠动脉降支出现假性动脉瘤。两次尝试栓塞假性动脉瘤均失败。剖腹手术时,在清除血凝块后发现了左结肠动脉的假性动脉瘤。然后切除假性动脉瘤,并修复左结肠动脉降支的侧方裂口。脓液在氢氧化钾涂片上显示有分隔菌丝。由于培养显示有黄曲霉生长,他接受了两性霉素B注射和口服伏立康唑治疗。最初肠梗阻阶段形成的早期纤维性、“易分离”的脆弱粘连,可能在拔除Tenckhoff导管时因牵拉而导致假性动脉瘤的形成。Tenckhoff导管的拔除、血红蛋白下降和腹部膨胀在时间上密切相关,因此因导管牵拉拔除导致假性动脉瘤这一点是不可否认的。一项对照试验将为支持或反对正式解剖拔除Tenckhoff导管提供确凿证据。