Qian Bang-Ping, Qiu Yong, Wang Bin, Yu Yang, Zhu Ze-Zhang, Zhu Feng, Ma Wei-Wei
Department of Spinal Surgery, Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China
Zhonghua Wai Ke Za Zhi. 2008 Jul 1;46(13):977-80.
To investigate early recognition and clinical evaluation of spontaneous spinal epidural hematoma (SSEH) and to analyze the factors related to prognosis.
Nine patients with SSEH were include in current study. There were 7 men and 2 women with a mean age of 45.4 years (range, 18-83 years). Etiological factors were noted in 9 patients, 3 with hypertension, 2 with angioma, 2 with laminar osteoblastoma, 1 with neuroblastoma, and 1 with thrombolysis treatment. Six patients presented with acute onset of neck or back pain. Two patients initially presented with incomplete paralysis. One patient emerged with ascending bilateral lower extremity weakness and loss of sensation after thrombolysis treatment. Neurologic deficit was four as Frankel A, two as Frankel B, one as Frankel C and two as Frankel D. Evacuation of the hematoma was carried out in eight patients. One patient of thrombolysis treatment was treated conservatively because of loss of optimum for operation.
Eight hematomas were located in thoracic region, one was found in the cervicothoracic region. Mean extension was 3.7 segments (range, 2-8 segments). One patient died of severe pulmonary infection 50 days postoperatively. The average follow-up observation was 7. 5 months. Evaluation of the neurological function showed that 2 patients being classified as Frankel B, 1 as Frankel D and 4 patients as Frankel E. There was no improvement of neurological function in 1 patient with conservative treatment.
The keys to the early diagnosis of SSEH are the characteristic of clinical symptoms, and the lesion site, the extent of the lesion demonstrated by MRI. The prognosis is worse for SSEH with etiological factor of hypertension. Early diagnosis and surgical treatment might get better results for SSEH resulting from tumour.
探讨自发性脊髓硬膜外血肿(SSEH)的早期识别与临床评估,并分析其预后相关因素。
本研究纳入9例SSEH患者。其中男性7例,女性2例,平均年龄45.4岁(范围18 - 83岁)。记录9例患者的病因,3例为高血压,2例为血管瘤,2例为骨母细胞瘤,1例为神经母细胞瘤,1例为溶栓治疗后。6例患者急性起病,表现为颈部或背部疼痛。2例患者最初表现为不完全性瘫痪。1例患者在溶栓治疗后出现双侧下肢进行性无力和感觉丧失。神经功能缺损按Frankel分级,A级4例,B级2例,C级1例,D级2例。8例患者进行了血肿清除术。1例溶栓治疗患者因失去最佳手术时机而采取保守治疗。
8例血肿位于胸段,1例位于颈胸段。平均累及节段数为3.7个(范围2 - 8个节段)。1例患者术后50天死于严重肺部感染。平均随访7.5个月。神经功能评估显示,2例为Frankel B级,1例为Frankel D级,4例为Frankel E级。1例保守治疗患者神经功能无改善。
SSEH早期诊断的关键在于临床症状特点、病变部位以及MRI显示的病变范围。高血压作为病因的SSEH预后较差。对于肿瘤导致的SSEH,早期诊断并手术治疗可能取得更好的效果。