Hanafy Enas, Elhafez Salam, Aly Fadel, Elazhary Mohamed
Faculty of Physical Therapy, Cairo University, Cairo, Egypt.
Electromagn Biol Med. 2008;27(4):402-8. doi: 10.1080/15368370802473505.
This study investigates the effect of whole body exposure to magnetic fields on the calcium level of blood and bone in a trial to avoid the liability of osteoporosis, fractures, and delayed union of fractures after exposure to magnetic fields present everywhere in the environment. The procedures of the study included analysis for calcium level in both bone and blood. The procedures were performed on 50 Guinea pigs equally divided into 5 groups. Groups A, B, C, and D were exposed to 50 Hz, 0.2 mT magnetic field for 30 d. Group E animals were the control. Group A was sacrificed immediately after exposure; Group B was left away from the field for 15 d for spontaneous repair; Group C received the drug Centrum dissolved in drinking water for 15 d after exposure to the magnetic field; and Group D received centrum in drinking water during the period of exposure (30 d). After sacrificing all animals, the calcium level in both bone and blood was evaluated. Values of blood analysis revealed significant increase in the blood calcium level in exposed animals compared with the control group (P < 0.002) with excess in Group A. This indicated that the calcium left the bone to the blood. Values of the bone analysis revealed significant decrease in bone calcium concentration level in Group A compared with the control group and improvement in the bone condition in Groups C and D, indicating the role of trace element after the exposure period as a compensatory agent of magnetic field damage and its role during the exposure period as a radio-protecting agent.
本研究旨在探究全身暴露于磁场对血液和骨骼钙水平的影响,以避免在环境中普遍存在的磁场暴露后出现骨质疏松、骨折及骨折延迟愈合等问题。该研究的步骤包括分析骨骼和血液中的钙水平。研究过程中选取了50只豚鼠,将其平均分为5组。A、B、C、D组暴露于50Hz、0.2mT的磁场中30天。E组动物作为对照组。A组在暴露后立即处死;B组在离开磁场15天后进行自然修复;C组在暴露于磁场后,饮用溶解有善存片的水15天;D组在暴露期间(30天)饮用含有善存片的水。处死所有动物后,评估骨骼和血液中的钙水平。血液分析结果显示,与对照组相比,暴露组动物的血钙水平显著升高(P<0.002),A组升高更为明显。这表明钙从骨骼转移到了血液中。骨骼分析结果显示,与对照组相比,A组的骨钙浓度水平显著降低,而C组和D组的骨骼状况有所改善,这表明暴露期后微量元素作为磁场损伤补偿剂的作用,以及其在暴露期作为辐射防护剂的作用。