Kongstad Johanne, Hvidtfeldt Ulla Arthur, Grønbaek Morten, Jontell Mats, Stoltze Kaj, Holmstrup Palle
Department of Odontology, University of Copenhagen, Copenhagen, Denmark.
J Clin Periodontol. 2008 Dec;35(12):1032-9. doi: 10.1111/j.1600-051X.2008.01325.x.
The aim of this study was to study the association between alcohol consumption and periodontitis assessed as clinical attachment loss (CAL) and bleeding on probing (BOP) in a cross-sectional design.
The study included 1,521 adults aged 20-95 years, who underwent an oral examination including full-mouth registration of CAL and BOP. Alcohol was ascertained using a food-frequency questionnaire. The association between total and type-specific alcohol and periodontitis was assessed by means of multivariate logistic regression.
A lower odds ratio (OR) for CAL (defined as mean >or=3 mm) was observed in men consuming 21-34 [OR=0.51, 95% confidence interval (CI), 0.27-0.95] and 35+ drinks/week (OR=0.34, 95% CI, 0.15-0.79) compared with men drinking 1-13 drinks/week. Also, men with a weekly wine consumption of more than 14 drinks compared with men who reported no wine intake had lower OR for CAL (OR=0.24; 95% CI, 0.09-0.62). A higher OR for BOP (defined as >or=25%) among male abstainers was observed (OR=1.79, 95% CI, 1.03-3.12) compared with men in the light-drinking group (1-13 drinks/week). No significant association was observed for either CAL or BOP in women.
The results indicate that higher alcohol consumption, particularly intake of wine, is inversely associated with CAL in men. Such an association is not found in women.
本研究旨在采用横断面设计,研究饮酒与牙周炎之间的关联,牙周炎通过临床附着丧失(CAL)和探诊出血(BOP)进行评估。
该研究纳入了1521名年龄在20 - 95岁之间的成年人,他们接受了口腔检查,包括全口CAL和BOP记录。通过食物频率问卷确定饮酒情况。采用多因素逻辑回归评估总饮酒量及特定类型酒精与牙周炎之间的关联。
与每周饮用1 - 13杯酒的男性相比,每周饮用21 - 34杯[比值比(OR)=0.51,95%置信区间(CI),0.27 - 0.95]和35杯及以上酒的男性中,CAL(定义为平均值≥3mm)的OR较低。此外,每周饮用超过14杯葡萄酒的男性与未报告饮用葡萄酒的男性相比,CAL的OR较低(OR = 0.24;95% CI,0.09 - 0.62)。与轻度饮酒组(每周1 - 13杯酒)的男性相比,男性戒酒者中BOP(定义为≥25%)的OR较高(OR = 1.79,95% CI,1.03 - 3.12)。在女性中,未观察到CAL或BOP有显著关联。
结果表明,较高的酒精摄入量,尤其是葡萄酒摄入量,与男性的CAL呈负相关。在女性中未发现这种关联。