Coppen Ann Marie, Risser Joseph A, Vash Peter D
Lindora Inc., Costa Mesa, CA 92626, USA.
J Cardiometab Syndr. 2008 Fall;3(4):205-10. doi: 10.1111/j.1559-4572.2008.00016.x.
Without aggressive intervention, childhood obesity and the metabolic syndrome may result in lifelong physical consequences. Interventions that emphasize healthy eating and regular exercise are crucial to stop this epidemic and its ramifications. This paper discusses the incidence of the metabolic syndrome and cardiovascular risk factors before and after a weight loss program. A retrospective review was conducted in 135 children and adolescents (aged 6 to 19) who completed a 10-week medically supervised weight loss program. Outcome measures included mean change in each component of the metabolic syndrome, total cholesterol, low-density lipoprotein cholesterol, and hemoglobin A(1c). After 10 weeks of weight loss, a mean (SD) weight loss of 9.24 (19.5) kg was attained. Resolution of the metabolic syndrome was seen in 75.5% of children and adolescents. Weight loss can reverse metabolic syndrome and decrease cardiovascular risk in as little as 10 weeks.
若不进行积极干预，儿童肥胖和代谢综合征可能会导致终身身体问题。强调健康饮食和定期锻炼的干预措施对于阻止这一流行病及其后果至关重要。本文讨论了减肥计划前后代谢综合征的发病率和心血管危险因素。对135名完成了为期10周医学监督减肥计划的儿童和青少年（6至19岁）进行了回顾性研究。结果指标包括代谢综合征各组成部分、总胆固醇、低密度脂蛋白胆固醇和糖化血红蛋白A(1c)的平均变化。经过10周的减肥，平均（标准差）体重减轻了9.24（19.5）千克。75.5%的儿童和青少年代谢综合征得到缓解。体重减轻可在短短10周内逆转代谢综合征并降低心血管风险。
