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多学科治疗可降低肥胖青少年代谢综合征的危险因素。

Multidisciplinary therapy reduces risk factors for metabolic syndrome in obese adolescents.

机构信息

Department of Physical Education, Multiprofessional Nucleus of Obesity Study, State University of Maringa, Maringa, Paraná, Brazil.

出版信息

Eur J Pediatr. 2013 Feb;172(2):215-21. doi: 10.1007/s00431-012-1865-7. Epub 2012 Oct 25.

DOI:10.1007/s00431-012-1865-7
PMID:23097084
Abstract

This study aims to assess the effects of a 16-week multidisciplinary program of obesity treatment on the control of metabolic syndrome (MS) and dyslipidemia in obese adolescents. Eighty-six adolescents aged 10-18 years were allocated in either the intervention group (IG; n = 44) or control group (CG; n = 42). IG was submitted to a multidisciplinary intervention based on cognitive behavioral therapy that aimed to modify eating habits and exercise behavior. We analyzed, before and after the intervention period, anthropometric parameters, body composition, bone mineral density, cardiorespiratory fitness, blood pressure, glucose, insulin, and lipid profile of the subjects. MS was classified according to International Diabetes Federation (2007) and the presence of dyslipidemia according to Back et al. (Arq Bras Cardiol 85:4-36, 2005). In the beginning of the intervention, the median number (range) of risk factors for MS present was 2.0 (0.0-5.0) in the IG and 2.0 (0.0-4.0) in the CG. After the intervention, this parameter reduced significantly in the IG (1.0 (0.0-5.0); p = 0.004) while no change was observed in the CG (2.0 (0.0-4.0); p = 0.349). In addition, we observed improvements in body mass index, waist circumference, hip circumference, maximal oxygen uptake, absolute and relative body fat, systolic blood pressure, diastolic blood pressure, and total cholesterol in the IG which was not identified in the CG. Conclusio n: We suggest that a 16-week multidisciplinary intervention based on cognitive behavioral therapy was adequate to reduce risk factors for MS in obese adolescents.

摘要

本研究旨在评估 16 周的肥胖治疗多学科方案对肥胖青少年代谢综合征(MS)和血脂异常控制的影响。86 名年龄在 10-18 岁的青少年被分为干预组(IG;n=44)或对照组(CG;n=42)。IG 接受基于认知行为疗法的多学科干预,旨在改变饮食习惯和运动行为。我们分析了干预前后,受试者的人体测量参数、身体成分、骨密度、心肺适能、血压、血糖、胰岛素和血脂谱。MS 根据国际糖尿病联合会(2007 年)进行分类,血脂异常根据 Back 等人的标准(Arq Bras Cardiol 85:4-36, 2005 年)进行分类。在干预开始时,IG 中 MS 的危险因素中位数(范围)为 2.0(0.0-5.0),CG 中为 2.0(0.0-4.0)。干预后,IG 中这一参数显著降低(1.0(0.0-5.0);p=0.004),而 CG 中则没有变化(2.0(0.0-4.0);p=0.349)。此外,我们观察到 IG 中体重指数、腰围、臀围、最大摄氧量、绝对和相对体脂、收缩压、舒张压和总胆固醇的改善,而 CG 中则没有观察到这些改善。结论:我们建议,基于认知行为疗法的 16 周多学科干预足以减少肥胖青少年 MS 的危险因素。

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