一名患有慢性假性肠梗阻儿童中Cajal间质细胞缺失。
Absence of the interstitial cells of Cajal in a child with chronic pseudoobstruction.
作者信息
Struijs Marie-Chantal, Diamond Ivan R, Pencharz Paul B, Chang Kenneth T E, Viero Sandra, Langer Jacob C, Wales Paul W
机构信息
Group for Improvement of Intestinal Function and Treatment (GIFT), The Hospital for Sick Children, Toronto, Canada M5G 1X8.
出版信息
J Pediatr Surg. 2008 Dec;43(12):e25-9. doi: 10.1016/j.jpedsurg.2008.09.017.
Absence or altered distribution of the interstitial cells of Cajal (ICCs) has been described in association with intestinal pseudoobstruction in adults. We report the first pediatric case with regional absence of ICCs in the distal small bowel and colon associated with intestinal pseudoobstruction. This report highlights that abnormalities of the ICCs in intestinal pseudoobstruction should be considered early in the diagnostic workup of children with intestinal pseudoobstruction.
在成人中，已发现空肠弯曲菌间质细胞（ICCs）缺失或分布改变与肠道假性梗阻有关。我们报告了首例远端小肠和结肠区域ICC缺失并伴有肠道假性梗阻的儿科病例。本报告强调，在对患有肠道假性梗阻的儿童进行诊断检查时，应尽早考虑肠道假性梗阻中ICC的异常情况。
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