Marmara University School of Medicine, Department of Emergency Medicine, Tophanelioglu C Yurtacan S No 13-15. Altunizade/Istanbul, Turkey.
Neuropsychiatr Dis Treat. 2008 Aug;4(4):711-4. doi: 10.2147/ndt.s3007.
Available data suggest that Parkinson's disease (PD) patients have a significant socioeconomic impact owing partly to increased hospital and drug utilization. The aims of this study were to provide a profile of patients with PD who required admission to hospital and to determine the reasons for emergency admission.
Between September 1st, 2004 and August 31st, 2006, patients with PD who were admitted to our emergency department (ED) were included in the study. Patients with PD who were diagnosed by a neurologist formerly, and admitted to the ED with any reason constituted the study population. Demographical data, reasons for admission, years exposed to PD, number of admissions to the emergency department in the past 12 months, prior Hoehn and Yahr (H&Y) scores were recorded. H&Y was performed again for all patients 4 weeks after discharge.
Seventy-six patients with PD were included in the study. Reasons for admission to hospital were infectious diseases (31.6%), trauma (27.6%), cardiovascular emergencies (14.5%), cerebrovascular emergencies (11.8%), gastrointestinal emergencies (7.9%), and electrolyte disturbances (6.6%), respectively. There was no dependence between the time of exposure to PD and H&Y score. Number of emergency admittance in the last 12 months was independent from the last H&Y score (p = 0.297). However, there was a dependency between the reasons for emergency admittance and the H&Y scores (p = 0.023).
H&Y score is not dependent on the emergency admittance or on the outcome after discharge from the emergency department. The motor disability by itself cannot predict the whole picture of PD and the systemic complications leading to emergency admittance.
现有数据表明,帕金森病(PD)患者具有重大的社会经济影响,部分原因是医院就诊和药物使用增加。本研究旨在提供需要住院的 PD 患者的概况,并确定急诊入院的原因。
2004 年 9 月 1 日至 2006 年 8 月 31 日期间,我院急诊科收治的 PD 患者纳入本研究。本研究的研究人群为曾被神经科医生诊断为 PD,因任何原因被收入急诊科的患者。记录患者的人口统计学数据、入院原因、PD 暴露年限、过去 12 个月急诊就诊次数、既往 Hoehn 和 Yahr(H&Y)评分。所有患者出院后 4 周再次进行 H&Y 评分。
本研究共纳入 76 例 PD 患者。住院原因分别为感染性疾病(31.6%)、创伤(27.6%)、心血管急症(14.5%)、脑血管急症(11.8%)、胃肠道急症(7.9%)和电解质紊乱(6.6%)。PD 暴露时间与 H&Y 评分之间无相关性。过去 12 个月的急诊就诊次数与最后一次 H&Y 评分无关(p=0.297)。然而,急诊就诊原因与 H&Y 评分之间存在相关性(p=0.023)。
H&Y 评分与急诊就诊或急诊科出院后结局无关。运动障碍本身不能预测 PD 的全貌和导致急诊就诊的全身并发症。