Rowlands Rebecca J, Michaud Vincent, Heath Livio, Hutchings Geoff, Oura Chris, Vosloo Wilna, Dwarka Rahana, Onashvili Tinatin, Albina Emmanuel, Dixon Linda K
Institute for Animal Health, Pirbright, UK.
Emerg Infect Dis. 2008 Dec;14(12):1870-4. doi: 10.3201/eid1412.080591.
African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype II, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFV-contaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.
非洲猪瘟（ASF）在非洲广泛传播，但很少传入其他大洲。2007年6月，非洲猪瘟在格鲁吉亚的高加索地区得到确认，此后传播到了邻国。对2007年从格鲁吉亚家猪分离株基因组中扩增的DNA片段进行测序，并与其他非洲猪瘟病毒（ASFV）分离株进行比较，以确定该病毒的基因型。从4个基因组区域获得了序列，包括编码p72衣壳蛋白的B646L基因的一部分、编码p54和p30蛋白的完整E183L和CP204L基因，以及B602L基因的可变区。对这些序列的分析表明，2007年格鲁吉亚分离株与莫桑比克、马达加斯加和赞比亚流行的II型基因型分离株密切相关。疾病传播到格鲁吉亚的一种可能性是，猪食用了船上运来的受ASFV污染的猪肉，随后疾病在整个地区传播开来。
